PREVALENCE OF METABOLIC SYNDROME IN NEWLY DETECTED DIABETES MELLITUS TYPE 2
Journal Title: International Journal of Medical Science and Diagnosis Research (IJMSDR) - Year 2018, Vol 2, Issue 2
Abstract
Introduction: In worldwide metabolic syndrome being increasing as a epidemic and also major risk factor for CVD and other vascular events like stroke. Last few decades infectious disease is decreasing in global whereas burden of chronic diseases (e.g. CVD and Diabetes) is on the rise. Metabolic syndrome is defined as a clustering of key cardiovascular risk factors like dyslipidemia, abdominal obesity, hypertension and hyperglycemia. The metabolic syndrome with the individuals also differs by sex, race, and ethnicity. Most of the people having metabolic syndrome was estimated prevalence of 62.4 per cent for Mexican Americans, 69.9 per cent for Whites and 64.8 per cent for Blacks. For coronary artery disease (CAD) and stroke, Type 2 diabetes mellitus (T2DM) is major risk factor. Low HDL cholesterol and High triglyceride levels significantly related to coronary heart disease and to coronary mortality in patients with T2DM. According to Third National Health and Nutrition Examination Survey (NHANES III) data, people not having metabolic syndrome had the lowest risk for cardiovascular disease (CVD) whereas people with metabolic syndrome had an intermediate level of risk and with diabetes had the highest level of risk. Aim: The main aim is to find the prevalence of metabolic syndrome in newly detected cases of type 2 diabetes mellitus. Material and methods: This study was conducted in Department of General Medicine of K.M. Medical College and Hospital, Mathura (UP). India during 1 year. Total 100 patients were included in this study who were diagnosed with newly detected Type 2 Diabetes Mellitus. These studies were perform after the approved by the Institute's Ethics Committee. With the help of clinical history, examination and investigations data was collection. Patients with more than 25 year of age with physical and history with clinical findings of Type 2 Diabetes Mellitus were including in this study. From all the patient’s Blood samples were taken after a minimum of nine hours of fasting then were asked to have a light fat free diet on the day prior to sampling. On the same day the samples were analyzed for the levels of trigycerides, HDL, LDL, and total cholesterol levels. Result: According to age, 45 patients were in age group of 30- 49 yrs, 36 patients in 50-59 yrs, 12 patients in 60-69 yrs and 7 patients in more than 70 years. As comparing age among male and female, mean age of all patients is 49.15 and Z valve is 0.53, p>0.05. According to the age group 30-49 yrs, 38 (44%) patients were predicting MS and 6 (7%) patients were predicting MS more than 70 years. 33 (38.4%) patients and 9 (10.5%) patients were follow in the group 50-59 years and 60 respectively predicting MS. This study showed more number of newly detected diabetes predicting MS were 30-49 years and least in more than 70 years. Mean age of male is 47.2±9.5, mean age of female is 49.6±10.3, and mean age of all cases is 48.6±10.5. Comparing this age mean age of all cases is 48.6±10.4. Various parameters of MS in newly detected DM patients as high Triglycerides present in 68(79%) patients where male by raised SBP in 58(67.4%) patients where male High fasting blood glucose was present in 55 patients and low HDL in 53 patients. Conclusion: Conclusion: In newly detected type 2 DM patients’ occurrence of MS was predicted highest. Decreased HDL for women and raised serum TG for men were strongest predictors which indicating effectively presence of MS in newly detected type 2 DM patients. Keywords: Diabetes Mellitus, Metabolic Syndrome, High-Density Lipoprotein, Triglycerides
Authors and Affiliations
Dr. Ashok Singh
Keywords
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