Prevalence of Non-Alcoholic Fatty Liver Disease in the Patients Suffering From Diabetes Mellitus Type II
Journal Title: Isra Medical Journal - Year 2018, Vol 10, Issue 5
Abstract
OBJECTIVE: To assess the prevalence of non-alcoholic fatty liver disease in type II diabetes mellitus patients. STUDY DESIGN: A Prospective Observational Study PLACE AND DURATION: Department of Medicine Nishtar Hospital Multan, from 1st April, 2017 to 1st January, 2018. METHODOLOGY: Patients presenting with diabetes mellitus type II were divided into two equal groups on the basis of presence or absence of non alcoholic fatty liver disease. Age, gender, BMI, Plasma aspartate aminotransferase, Plasma alanine aminotransferase, Plasma alkaline phosphatase, duration of type II diabetes mellitus, fasting plasma glucose, serum albumin, plasma cholesterol, plasma triglycerides, Plasma LDL-C, Plasma HDL-C and HbA1c were the variables calculated. RESULTS: The mean age was 59.15±5.63 years, BMI 32.03±5.32 kg/m2, Plasma AST 19.68±2.22, Plasma ALT 19.87±1.71, Plasma ALP 62.32±12.84, duration of type 2 DM was 8.40±3.71 years and fasting plasma glucose of non NAFLD patients was 124.57±5.66 mg/dl. While, the mean age was 61.55±8.00 years, BMI 32.05±6.24 kg/m2, plasma AST 23.03±2.56, plasma ALT 27.28±1.94, plasma ALP 75.19±21.30, duration of type 2 DM 8.12±1.28 years and fasting plasma glucose of NAFLD patients was 137.45±5.07 mg/dl. The mean albumin (g/dl) was 4.20±0.64 g/dl, plasma cholesterol was 150.65±28.44, plasma triglyceride 114.04±5.99, plasma LDL-C 87.25±18.16 and plasma HDL-C of non NAFLD patients was 42.97±11.40. HbA1c in non NAFLD was 9.1%. While, the mean albumin was (g/dl) 3.80±0.69 g/dl, plasma cholesterol 158.62±42.02, plasma triglyceride 150.07±9.03, plasma LDL-C 87.0±27.89 and plasma HDL-C of NAFLD patients was 40.76±10.46. HbA1c of NAFLD patients was 6.8%. CONCLUSION: Non alcoholic fatty liver disease has a high prevalence in patients with type II diabetes mellitus having normal aminotransferases. KEYWORDS: Prevalence, Non-Alcoholic Fatty Liver Disease, Diabetes Mellitus, Non-Alcoholic Steatohepatitis, Aminotransferases, Alanine Aminotransferase, Aspartate Aminotransferase, Plasma Glucose HOW TO CITE THIS: Athar MM, Rasheeq T, Ahmed M, Furqan A. Prevalence of Non Alcoholic Fatty Liver Disease in the Patients Suffering From Diabetes Mellitus Type II. Isra Med J. 2018; 10(5): 263-266.
Authors and Affiliations
Muhammad Mumtaz Athar
Keywords
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