Prevalence of TB associated chronic obstructive pulmonary disease in patients with COPD attending at tertiary care hospital in Ahmedabad: A case control study
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 2
Abstract
Background Apart from tobacco smoke COPD has been known to occur in patients with previous pulmonary TB Present study was performed with an aim to conduct a study to discover out the hospital based prevalence of TBassociated COPD among COPD patients and to assess its distinguishing features in Ahmedabad Gujarat IndiaPresent study was conducted at the Department of Tuberculosis and Reparatory Medicine in a tertiary care hospital over a period of 7 months Seventyfour consecutive patients of stable COPD attending chest OPD were enrolled as cases An equivalent number of healthy subjects with comparable age and gender distribution were taken as controls Specific points such as number of antitubercular treatment ATT courses total duration of treatment time elapsed since completion of treatment and their final outcome were recorded The prevalence of TBassociated COPD group was calculated and its different parameters were compared with rest of COPD patientsResults Median duration of onset of symptoms was 41 years The unadjusted odds ratio for previous TB in the COPD group in comparison to controls was 395 Most of the patients 2124 had taken a single course of ATT TBassociated COPD patients were significantly younger in age as compared to the rest of COPD patients P le 005 with more proportion of females On multivariate analysis duration of dyspnea retained positive correlation with hospitalizations after adjusting for pack years age and BMIConclusions TBassociated COPD constitutes a substantial proportion of COPD in a hospital setting It is a distinct clinical entity different from a larger smoking related COPD and hence may require different managementKeywords COPD Odds ratio Prevalence TB
Authors and Affiliations
Gunjan Upadhyay, Pradipkumar Damor
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