Prevalence of vitamin D deficiency in adults in the coastal regions of Odisha, India
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
Background and objectives: Vitamin D is a fat-soluble vitamin belonging to secosteriods. It is responsible for intestinal absorption and bioavailibity of calcium and phosphorus.Synthesisof vitamin D in response to ultraviolet rays in skin depends on latitude, atmospheric pollution, clothing, skin pigmentation, sunscreen usage, duration and time of exposure to sunlight. Deficiency causes rickets, defective bone mineralization, osteomalacia and various non skeletal diseases such asrheumatoid arthritis, diabetes mellitus, coronary artery disease and cancer. Recent studies have suggested a deficiency state in Indian populationinspite of ample sunshine. Hence, this study was designed to estimate the prevalence of vitamin D deficiency in adults in the coastal regions of Odisha, India Material and methods: This cross-sectional study included 3056 conducted among healthy population of Cuttack, a coastal district of Odisha. All the individuals were tested for serum 25(OH)D level by electrochemiluminescense immunoassay method using automated analyzer Cobas e411, Roche diagnostics. Results: We observed a vast majority of individuals (48.2%), were deficient and many were moderately (36.7%) deficient. Among the study population almost 84.9% were deficient in vitamin D. The deficiency was more in females (78.7%) as compared to males in this study population. Conclusion: We conclude by suggesting that regular serum vitamin D status must be assessed to review the nutritional status in apparently healthy population and in musculoskeletal diseases. Vitamin D supplementation may be introduced along with regular monitoring may be included in the health care management.
Authors and Affiliations
Roma Rattan, Duryodhan Sahoo, Srikrushna Mahapatra
Keywords
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- EP ID EP387026
- DOI 10.9790/3008-1106054952
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