Primary Liver Cancer in Adults
Journal Title: Current Trends in Gastroenterology and Hepatology - Year 2018, Vol 1, Issue 5
Abstract
Liver cancer includes two main types: hepatocellular carcinoma (HCC) and intrahepatic bile duct cancer. Incidence and mortality. Calculation of the number of new cases and deaths due to liver and intrahepatic bile duct cancer in the United States in 2018: I. New cases: 42 220. II. Deaths: 30 200. HCC is relatively rare in the United States, although its incidence is increasing, especially in regard to the spread of infection with the hepatitis C virus (HCV). HCC is the most common solid tumor in the world and the third leading cause of cancer-related deaths. Anatomical Characteristics: Anatomy of the liver. The liver is in the upper part of the abdomen, near the stomach, the intestines, the gall bladder and the pancreas. The liver has a right lobe and a left lobe. Risk Factor’s: The etiology of HCC is probably multifactorial. The following factors may increase the risk of CHC: Infection with the hepatitis B virus (HBV) and infection with the hepatitis C virus (HCV): HBV and HCV infections seem to be the most important causes of HCC in the world. Chronic HBV infection is the main cause of HCC in Asia and Africa. HCV infection is the main cause of HCC in North America, Europe and Japan. The annual incidence of HCC in HBV carriers is 0.5 to 1% per year in non- cirrhotic patients and 2.5% per year in cirrhotic patients. The relative risk of HCC is 100 (that is, HBV carriers are 100 times more likely to have HCC than people who are not infected) [1] In a single prospective population study that included 12 008 patients, the presence of positivity for anti-HCV increased the risk of HCC twenty-fold more than in anti- HCV negative people. HCC can occur in fibrosis patients on bridges, infected with HCV, even in the absence of overt cirrhosis. However, the highest risk is that of patients with confirmed cirrhosis related to HCV, which has an annual incidence rate of 2 to 8%. [2].
Authors and Affiliations
Mirta D Ambra
Keywords
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- EP ID EP570960
- DOI 10.32474/CTGH.2018.01.000122
- Views 51
- Downloads 0
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