Profile of Adverse Drug Reaction Related Hospitalization ina Tertiary Care Teaching Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Adverse drug reactions are a major problem worldwide and are one among the leading causes of morbidity and mortality. They are an important cause of hospitalization or prolongation of hospital stay. This study was conducted to find out the profile of ADR induced hospitalization in our tertiary care teaching hospital. A prospective, observational study was conducted over a period of 10 months in the department of Medicine. Cases admitted with suspected ADR in the in-patient department of Medicine were included in the study. The results showed that ADR related hospitalizations accounted for 0.24% of the total admissions to the Medicine department. Elderly male patients outnumbered females. Hypoglycemia was the commonest ADR, followed by other systems (Cutaneous, GI, CNS). Insulin and sulfonylureas were themost common suspected medications followed by antimicrobials, NSAIDS and antiplatelets. Polytherapy was the most common predisposing factor. Only 10% of ADR induced hospitalization were due to self-medication and rest 90% were due to prescribed medication.
Authors and Affiliations
Namita Mohapatra, Kali Prasad Pattnaik, Phillemon Ekka, Nirjharini Dhal, Jigyansa Mohapatra
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