PROFILE OF CASES OF INFECTIOUS MENINGITIS IN HIV PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 10
Abstract
BACKGROUND Central nervous system (CNS) involvement is one of the common manifestations of acquired immunodeficiency syndrome (AIDS). About one-fifth of AIDS patients die of CNS diseases. MATERIALS AND METHODS A hospital-based cross-sectional descriptive study was conducted in Rajiv Gandhi Institute of Medical Sciences, Ongole. 50 HIV patients with clinical features suggestive of meningitis were selected for the study. A brief history and detailed investigations were carried out for the patients. RESULTS Out of the 50 study population, majority (56%, n= 28) belonged to 30 - 39 years’ age group and majority (60%, n= 30) were females. Tuberculous meningitis was found to be the most common cause of meningitis in HIV patients. In the present study, 30 patients (60%) were found to have tuberculous meningitis and 5 patients (10%) were found to have cryptococcal meningitis. 46 patients had CD4+ T-cell count < 500/uL, among whom 18 patients had CD4+ T-cell count < 200/uL. All the patients with tuberculous meningitis and cryptococcal meningitis were found to have CD4 count < 500/uL. CONCLUSION Tuberculous meningitis was found to be the most common cause of meningitis in HIV patients
Authors and Affiliations
Yarram Rajeswara Rao, Gudi Srinivas
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