PROGNOSTIC EVALUATION OF CHRONIC LIVER DISEASE PATIENTS WITH VARIOUS SCORING SYSTEMS
Journal Title: International Journal of Current Research and Review - Year 2017, Vol 9, Issue 1
Abstract
Background: Prognostic evaluation of patients with chronic liver diseases is an important topic, often challenging the clinician. The number of patients on waiting lists for orthostatic liver transplantation (OLT) is becoming increasingly higher compared with the number of available donor livers. Correct timing of orthostatic liver transplantation can reduce the mortality of patients on waiting lists and improve post-transplantation survival. Objective: To evaluate the short and medium term survival prognosis of chronic liver disease patients by means of various scoring systems. Material and Methods: Our study was a hospital based retrospective study in which 93 chronic liver disease patients of either sex, age > 18 years and of any etiology were included. Medical records of these patients were retrospectively reviewed. Child-pugh, MELD, MELA-Na and updated forms of MELD and MELD-Na were calculated from data. Predictive value of survival at 3 months and 1 year were compared between scores through AUROC (Area under receiver operating characteristics and p value of < 0.05 was considered significant. Results: 23 patients died including 4 who lost follow up, but all where belonging to Child Pugh class C and so considered dead. At both levels of assessment the scores of patient who died where significantly higher than those who survived, but there was no statistically significant difference in prediction of survival between various scores at both times as shown by their AUROC. Conclusion: All these scoring systems are useful for predicting survival of chronic liver disease patients and so more studies are warranted to investigate the superiority of one model over others..
Authors and Affiliations
Dr. Abdul Qayoom
Keywords
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