Prognostic factors for mortality in pediatric acute poststreptococcal glomerulonephritis

Journal Title: Paediatrica Indonesiana - Year 2016, Vol 56, Issue 3

Abstract

Background Acute post-streptococcal glomerulonephritis (APSGN) is one of the most common causes of glomerular disease in developing countries, including Indonesia. It can lead to end stage renal failure and higher mortality rates. To decrease morbidity and mortality, it is important to understand the prognostic factors affecting the disease.Objective To identify prognostic factors affecting outcomes in pediatric APSGN patients.Methods Study data were collected from medical records of patients with APSGN hospitalized in Wahidin Sudirohusodo Hospital, Makassar in 2009-2013. Possible prognotic factors analyzed were gender, age, nutritional status, level of consciousness, as well as proteinuria, hemoglobin, serum albumin, urea, and creatinine levels.Results Of 86 subjects, 82 (95.3%) survived and 4 (4.7%) died. Fifty-three (61.6%) patients were male and 33 (38.4%) were female. Subjects’ ages ranged from 3.42 to 14.67 years, with a mean age of 9.36 years. Multivariate analysis revealed serum creatinine level >1.5 mg/dL to be an independent prognostic factor for mortality in children with APSGN (AOR 15.43; 95%CI 1.31 to 181.7; P=0.03).Conclusion High serum creatinine level is an independent prognostic factor for poor outcomes in children with APSGN. [Paediatr Indones. 2016;56:166-70.].

Authors and Affiliations

Syamsul Nur, Husein Albar, Dasril Daud

Keywords

Related Articles

Skin prick test reactivity in atopic children and their number of siblings

Background Some studies have shown that low birth order is a risk factor for developing atopy, although these results remain inconclusive. Those studies put forth the hygiene hypothesis, which states that early childhood...

Food allergies in children: a comparison of parental reports and skin prick test results

Background Food allergy is common in children and its prevalence is generally on the rise. Imprecise parental reports about reactions to particular foods can lead to unnecessary restrictions. Since children have specific...

Immunization competence retention in medical students: a comparation between conventional lectures and lectures with simulations method

Background Immunization is recognized as one of the strategies to reduce vaccine preventable diseases. Competency related to immunization are consequently important for medical students and the medical school needs to as...

Third trimester maternal 1,25-dihydroxyvitamin D and neonatal birth weight

AbstractBackground The main cause of neonatal mortality is low birth weight. Active form of vitamin D (1,25-dihydroxyvitamin D) increase the efficiency of calcium and phosphorous absorption in intestinal. Deficiency 1,25...

Effect of intravenous gentamicin on urinary calcium excretion in newborns

Background Studies in newborns and animals have shown that gentamicin increases urinary calcium excretion. New recommendation for gentamicin in newborns is administered intravenously 36-48 hourly. Subsequent to this new...

Download PDF file
  • EP ID EP446130
  • DOI 10.14238/pi56.3.2016.166-70
  • Views 83
  • Downloads 0

How To Cite

Syamsul Nur, Husein Albar, Dasril Daud (2016). Prognostic factors for mortality in pediatric acute poststreptococcal glomerulonephritis. Paediatrica Indonesiana, 56(3), 166-70. https://europub.co.uk./articles/-A-446130