Prognostic factors for mortality in pediatric acute poststreptococcal glomerulonephritis
Journal Title: Paediatrica Indonesiana - Year 2016, Vol 56, Issue 3
Abstract
Background Acute post-streptococcal glomerulonephritis (APSGN) is one of the most common causes of glomerular disease in developing countries, including Indonesia. It can lead to end stage renal failure and higher mortality rates. To decrease morbidity and mortality, it is important to understand the prognostic factors affecting the disease.Objective To identify prognostic factors affecting outcomes in pediatric APSGN patients.Methods Study data were collected from medical records of patients with APSGN hospitalized in Wahidin Sudirohusodo Hospital, Makassar in 2009-2013. Possible prognotic factors analyzed were gender, age, nutritional status, level of consciousness, as well as proteinuria, hemoglobin, serum albumin, urea, and creatinine levels.Results Of 86 subjects, 82 (95.3%) survived and 4 (4.7%) died. Fifty-three (61.6%) patients were male and 33 (38.4%) were female. Subjects’ ages ranged from 3.42 to 14.67 years, with a mean age of 9.36 years. Multivariate analysis revealed serum creatinine level >1.5 mg/dL to be an independent prognostic factor for mortality in children with APSGN (AOR 15.43; 95%CI 1.31 to 181.7; P=0.03).Conclusion High serum creatinine level is an independent prognostic factor for poor outcomes in children with APSGN. [Paediatr Indones. 2016;56:166-70.].
Authors and Affiliations
Syamsul Nur, Husein Albar, Dasril Daud
Keywords
Related Articles
- EP ID EP446130
- DOI 10.14238/pi56.3.2016.166-70
- Views 77
- Downloads 0
Correlation of renal volume to renal function and blood pressures in low birth weight children
Background Disruption of nephrogenesis in low birth weight(LBW) infant leads to decreases in nephron number andrenal volume, resulting in renal hyperfunction and eventually,hypertension.Objective To assess for a possible...
Preoperative intralesional injection of triamcinolone acetonide for a large head and neck lymphangioma in a baby: a case report
Lymphangiomas (LMs) are uncommon congenital malformations of the lymphatic system, with an estimated incidence of one in 2,000 to 4,000 live births.1 About half of these lesions are diagnosed at birth, and by two years o...
Acute kidney injury and mortality in critically ill children
Background Mortality from acute kidney injury (AKI) can be ashigh as 60% in critically ill children. This high mortality rate isinfluenced by the severity of primary diseases, organ dysfunction,and the stage of acute kid...
Soluble transferrin receptor levels in obese and non obese adolescents
Background Iron deficiency in children and adolescents maybe dueto an inadequate supply of iron as well as increased iron requirementsfor growth and developmental processes. The incr easing prevalence ofobesity puts chil...
Effectiveness of ferric sodium edentate supplementation in children with lead poisoning
Background Lead is a harmful toxin that affects human health worldwide, especially in children. Lead poisoning remains a global problem both in developed and developing countries. The Centers for Disease Control and Prev...