PROGNOSTIC INDICATORS AND PATTERNS OF RENAL RECOVERY IN PATIENTS REQUIRING HEMODIALYSIS FOR ACUTE KIDNEY INJURY
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2014, Vol 3, Issue 1
Abstract
Background: The outcome of patients with acute kidney injury (AKI) is highly variable. Patients who receive renal replacement therapy (RRT) for similar diseases may recover differently. The factors that operate in each patient may alter the prognosis and outcome. Aims: Our study aims at identification of prognostic factors influencing recovery in patients who required hemodialysis for AKI. Material and Methods: Patients admitted in different ICUs with AKI who underwent hemodialysis in a tertiary care hospital over a three year period were included in the study. Time from day one of disease to first dialysis, hematological and biochemical parameters were noted. Patients were grouped based on the time taken for recovery of renal function following hemodialysis into group A (<2 weeks) and group B (>2 weeks). Studied parameters have been statistically analyzed to find any significant association with recovery time. Results: Out of 63 patients, 9 progressed to chronic kidney disease. In the remaining 54, Group A comprised 31 and group B 23. Out of all the factors studied, serum creatinine (7.0±1.3 vs 8.4±3.8; P=0.018), S. bicarbonate (21.7±2.8 vs 19.7±3.8; P=0.03), pH at admission (7.25±0.13 vs 7.1±0.19; P=0.048); number of hemodialysis sessions (3.5 ±1.5 vs 5±2.4; P=0.016) and time lag from day one of disease to first hemodialysis (8.6 ± 3.6 vs 11.5±5.9; P=0.007) showed significant association with recovery time. Conclusion: Recovery following AKI is influenced by factors liked delayed presentation, late initiation of hemodialysis, low pH and low bicarbonate which can predict delayed renal recovery following hemodialysis.
Authors and Affiliations
Vaddadi Suresh| Associate professor, Dept of Medicine, GSL General Hospital, Rajahmundry, Andhra Pradesh, India, Corresponding author email: sureshvaddadi@yahoo.co.in, Usha Bhargavi E| Assistant professor, Dept of Pathology, GSL General Hospital, Rajahmundry, Andhra Pradesh, India, N. S. R. C Guptha| Assistant professor, Dept of Medicine, GSL General Hospital, Rajahmundry, Andhra Pradesh, India, Vinod L| Post Graduate, Dept of Medicine, GSL General Hospital, Rajahmundry, Andhra Pradesh, India, Vijay Kumar P| Professor; Dept of Medicine, GSL General Hospital, Rajahmundry, Andhra Pradesh, India, Ravinder P| Consultant Nephrologist, Apollo hospitals, Kakinada, Andhra Pradesh, India
MEDICAL UNCERTAINTY: ARE WE BETTER OFF IN ERA OF EVIDENCE BASED MEDICINE?
Uncertainty is inherent to the medical profession. Medical profession incorporates science and the scientific method with the art of being a physician. Every decision a clinician makes has some degree of uncertainty in...
Comparison of the influence of acupressure and self-care behavior education on the severity of primary dysmenorrhea based on visual analogue scale among students
Dysmenorrhea is one of the frequently occurring problems which affect many young women’s life, and their efficiency and productivity. The aim is comparison of the effect of acupressure in two points of Guan Yuan (RN-...
Co-occurrence of Gardnerellavaginalis and Candida sp. in women with and without vulvovaginitis
Aims: To detect the co-occurrence of Gardnerellavaginalis and Candida sp.in women with and without vaginal symptoms. Methods: A cross-sectional study was performed in women seeking treatment in a Brazilian city from Ma...
EVALUATION OF BRAINSTEM AUDITORY EVOKED POTENTIAL IN MIGRAINE PATIENT
Background: Migraine is worldwide common, chronic, Neurovascular disorder, characterized by attacks of severe headache and an Aura involving neurologic symptoms. Its pathogenesis was incompletely understood whether of...
Changes in some of the indicators of liver inflammation and cardiovascular risk factors during a term of synthetic aerobic exercise of diabetic women
People with type II diabetes have more liver function abnormalities than non-diabetics. Recent studies have shown the mutual relationship between metabolic conditions of type II diabetes and non-alcoholic fatty liver di...