Pseudo-outbreak of Burkholderia cepacia blood stream infections in intensive care units of a super-speciality hospital: A cross-sectional study
Journal Title: International Journal of Medical Science and Public Health - Year 2017, Vol 6, Issue 7
Abstract
Background: Multiple nosocomial outbreaks caused by Burkholderia cepacia involving contaminated water, contaminated medication, nebulization solution, etc., have been reported. Objectives: This study was conducted with the aim of tracing the most likely causes of sudden increase in isolation rates of B. cepacia from blood samples of patients admitted in different intensive care units (ICUs) of a super-speciality hospital. Materials and Methods: A cross-sectional study was conducted in a super-specialty hospital located in New Delhi, India, from August 2015 to July 2016. Blood samples from 600 non-consecutive patients admitted in various ICUs were received for culture and sensitivity testing during the study period. Blood samples of 147 of these non-consecutive inpatients yielded B. cepacia in culture. Relevant details of all patients were obtained as per the pro forma formulated. Environmental sampling was also performed at regular intervals to trace the possible sources of infection. Chi-square test was used to calculate P value. Results: The study period was divided into three-quarters and the difference in the proportion of cases isolated from the ICUs under study during each of these quarters was not found to be statistically significant (0.05 < P < 0.1). A statistically significant association (P < 0.001 using Chi-square test) was found between afebrile status and simultaneous isolation of B. cepacia from blood samples of patients. B. cepacia could not be consistently isolated from any source during the study period. Conclusions: Nursing staff and doctors working in wards and ICUs should work in liaison with a diagnostic laboratory to assure swift communication of healthcare-associated infection alerts. Isolation of B. cepacia from clinical samples should always be correlated clinically to avoid inadvertent use of antimicrobials.
Authors and Affiliations
Mohit Bhatia, Poonam Sood Loomba, Bibhabati Mishra, Vinita Dogra
Keywords
Related Articles
- EP ID EP317602
- DOI 10.5455/ijmsph.2017.0305723032017
- Views 79
- Downloads 0
Association between eating habits and body mass index (BMI) of adolescents
Background: Adolescent’s eating habits and weight status is a cumulative effect of the health and nutritional problems occurring during early childhood as well as those originating in adolescence. Aims & Obje...
Maternal health challenges of pregnant women living on construction sites in Mumbai, Navi Mumbai, and Thane: A mixed-methods study
Background: Of the estimated 30 million construction workers in India 51% are women, however, there are no studies on pregnant women living on construction sites in the Indian population. Objective: The present study was...
Awareness to health hazards and biosafety precautions among laboratory technicians working in tertiary-care center in Rajasthan, India
Background: Awareness to health hazards and biosafety precautions among laboratory workers is an important aspect. Technicians handle blood or any biological sample may be at risk for accidental injury or exposure. The...
A Community based cross sectional study of dog bites in children in a rural district of Tamil Nadu
Background: Worldwide dog bites are becoming a significant public health problem and the annual frequency of dog bite injuries in children is estimated to be 22 per 1000 children of which less than half of them are repor...
Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India
Background: Hepatitis C is endemic in most parts of the world. It is a blood borne infection, which has a significant impact in treatment and outcome of renal failure patients undergoing dialysis. Objective: To d...