Purple glove syndrome: A potentially serious complication of phenytoin

Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 5

Abstract

Purple Glove Syndrome is a grave complication of intravenous phenytoin administration that is unfamiliar to many in the medical profession. It presents with edema, pain and bluish-purple discolouration of the limb and can lead to gangrenous changes in severe cases. Mild cases can be managed conservatively, with a positive outcome, whereas severe cases may require surgical treatment. Ignorant medical practitioners may have to face medicolegal complaints of this complication; wrongly attributed to mismanagement, overdosing and improper intravenous cannulation or extravasation. In the past Purple Glove Syndrome has been reported majorly in adult and elderly patients. However, we report a case of a three year old male child with Purple Glove Syndrome who had to undergo left upper limb-below elbow amputation due to the setting in of gangrene.

Authors and Affiliations

Dr. Bela Verma

Keywords

Related Articles

Adsorption behavior of methylene blue onto gellan gum-bentonite composite beads for bioremediation application

Biopolymer Gellan Gum (GG) was made into insoluble composite bead using Bentonite (BT), a clay material. This insoluble composite formation was carried out using ionotropic gelation method where calcium chloride was a cr...

Phytochemical analysis, antibacterial property and molecular docking studies of Mammea suriga kosterm

Mammea suriga is an endemic, medicinal and economically important tree belonging to the family Callophyllaceae, distributed along the Western Ghats of India. The present study focuses on phytochemical aspects, antibacter...

GCMS and FTIR analysis on the methanolic extract of red Vitis Vinifera seed

Vitis Vinifera seed is a member of vitaceae family which contains high phenolic procyanidins, Gallic acid, Catechin, Anthocyanin, Vitamin E, linoleic acid and flavonoids. Our present work aimed to identify the possible p...

Evaluation of in-vitro Antioxidant and Anti-diabetic activities of leave aqueous extracts of Oudneya Africana

The aim of this study was to investigate the biological properties, including antioxidant, anti-diabetic activity and phytochemical analysis of Oudneya Africana R. Br.. Qualitative analysis of phytochemicals (flavonoid,...

Complementary and alternative medicine use in children with haematological disorders

Objectives: To study pattern of complementary and alternative medicine(CAM) use in paediatric patients suffering from thalassemia and compare CAM use in patients of thalassemia and sickle cell disease(SCD). Methodology:...

Download PDF file
  • EP ID EP198682
  • DOI -
  • Views 100
  • Downloads 0

How To Cite

Dr. Bela Verma (2016). Purple glove syndrome: A potentially serious complication of phenytoin. World Journal of Pharmaceutical Sciences, 4(5), 285-287. https://europub.co.uk./articles/-A-198682