QTc Prolongation in Healthy Young Male Smokers Compared to Non-Smokers in Tertiary Care Centre
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 1
Abstract
Introduction: According to World Health Report (2002) tobacco is the most preventable cause of overall as well as cardiovascular mortality worldwide. It was calculable that there have been a hundred million deaths worldwide in the twentieth century. The whole range of tobacco users within the world has been calculable at 1.2 billion, that is predicted to rise to 1.6 billion throughout year 2020’s. At present, tobacco use causes death of 3.5 to four million folks globally and expected to extend concerning ten million throughout year 2020’s. It has also been estimated that by 2030, there will be more than 8 million deaths every year. Study aimed to evaluate QTc changes in apparently healthy young male smokers compared to non-smokers, using a 12 lead ECG record. Material and methods: 150 healthy young male Smokers and Non-smokers of same age group was included in the study. Total Duration of study was 24 months including Data Collection - 18 months (December 2015 to May 2017) and data analysing 6 months (June 2017 – November 2017) in a setting of Medicine OPD of Krishna institute of medical sciences, Karad. (Tertiary Care). Result: QTC interval was slightly higher among smokers than non-smokers and this was also found to be statistically significant. Conclusion: Smoking induces significant alteration in cardiac electrophysiology Prolongation of QTc interval in apparently healthy young individuals, which may predispose to cardiovascular morbidity and mortality in the long run. Smoking induced alterations manifest as significant variation in waveforms in ECG recordings of even asymptomatic smokers when compared to nonsmokers. ECG can be a used as a simple and inexpensive tool to assess smoking induced damage, and to counsel and motivate smokers to quit cigarettes.
Authors and Affiliations
Vasant Deokar, Mandade Arjun D, Makarand Mane, Dany P John, Divyen Kothia, Mohit Khatri
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