Quality Control Parameters of Arogyavardhini Rasa prepared by classical method
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2016, Vol 2, Issue 4
Abstract
Background: Arogyavardhini Rasa (AVR) is a well-known An Ayurvedic herbo-mineral formulation, indicated for treatment of broad spectrum chronic diseased conditions commonly used by physicians whose details of pharmaceutical processing are yet to document. Current research is first effort to document quality control parameters of this important formulation. Aim: To study the Pharmaceutical and physicochemical Quality Control Parameters profiles of Arogyavardhini Rasa. Materials & Method: AVR was prepared in one pilot and 3 main batches as per classical reference of Rasaratnasamucchaya. Its Physico-chemical parameters, qualitative tests for functional groups, Chromatography and quantitative elemental estimation were investigated. Results & Discussion: An average of 2500ml Swarasa was required for optimum Mardana for preparation of AVR from Avg. 506 gms of powdered Raw drugs, leading to an average yield, % yield (as that of powdered drugs) % wt gain of 605gm, 119.56%, 99 gm and 19.56% respectively. Functional groups Cardiac Glycosides, Alkaloids, Tannins and Phenols, Proteins, carbohydrates, steroids, Flavanoids, Saponins, Amino acids, Starch and Sugar were present. HPTLC study revealed a total of 11 and 8 bands at 254 nm and 366 nm in AVR. Conclusion: There is uniformity among results of observed and test parameters, among 3 batches. Pharmaceutical process, Results of pharmaceutical study, Physico-chemical tests, Presence of functional groups and HPTLC profile in present study may be considered as Standard manufacturing process of Arogyavardhini Rasa.
Authors and Affiliations
Yuga Raj Sapkota*, Prashant Bedarkar, V. J. Shukla, P. K Prajapati
Keywords
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