Quality of medicinal maltose as a excipient in the production of blood products: a comparative study
Journal Title: Chinese Journal of Blood Transfusion - Year 2024, Vol 37, Issue 5
Abstract
Objective To comprehensively compare the quality and filtration efficiency of medicinal maltose between two domestic manufacturers(B, C) and one foreign manufacturer(A), compare their product quality as an excipient for intravenous immunoglobulin(IVIG), so as to determine the feasibility and substitutability of maltose as an excipient for IVIG from different manufacturers. Methods Quality inspection and comparison of maltose from different manufacturers, small-scale filtration tests, and product quality comparision of IVIG(pH4) were conducted. Results The comparis on results showed that there was no significant difference in the quality of medicinal maltose between manufacturer B and A, and there was no significant difference in the quality of IVIG (pH4) produced. The quality of manufacturer C did not meet the requirements. Conclusion There is no significant difference in the quality of medicinal maltose produced by manufacturer B and A, which can be used for the production of IVIG (pH4).
Authors and Affiliations
Zhiru DU, Jie HUANG, Yingqiu TAO, Hui ZHANG, Chao LUO, Yaling DING
Keywords
Related Articles
- EP ID EP738824
- DOI 10.13303/j.cjbt.issn.1004-549x.2024.05.015
- Views 52
- Downloads 0
Serological characteristics of anti-PP1Pk and literature review on P blood group system
Objective To comprehensively explore the serological characteristics of anti-PP1Pk and potential therapeutic strategies for recurrent miscarriage in p-blood type pregnant women. Methods Neutralization with pigeon egg whi...
Polymorphism study of HLA-A, B, DRB1 alleles in patients with chronic renal failure, in Shandong Peninsula
Objective To investigate the association between HLA-A, B, DRB1 alleles and chronic renal failure (CRF) in Han population of Shandong Peninsula. Methods Sequence specific oligonucleotide probe-polymerase chain reaction (...
Research progress of neonatal low-threshold platelet transfusion strategy
Neonatal thrombocytopenia is one of the common hematological abnormalities in neonates, especially premature infants. Platelet transfusion is an effective method of treating neonatal thrombocytopenia, but its threshold s...
Survey on the willingness to re-donate blood and its influencing factors of street blood donors
Objective To investigate the re-donation willingness and its influencing factors of street blood donrs, so as to stable the team of blood donors and enhance the efficiency of blood collection. Methods From July 2021 to D...
K antigen serological screening results in 20 354 population from Qingdao area
Objective To perform serological screening of K antigen in Qingdao area and analyze the results. Methods From March to June 2023, 16 201 samples of patients treated in our hospital and applied for blood grouping, and 4 1...