QUANTIC CHEMICAL ANALYSIS OF THE INTERACTION OF CORTISONE, INSULIN AND GLUCOSE
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 6
Abstract
In recent years, doctors have linked the dosage of Cortisone (CTS) as a cause of hyperglycemia in patients. The objective of this research is to study the interaction of glucose, insulin, and as a cause of hyperglycemia in humans. The hyperchem quantum simulator and specifically the Semi-Empirical Parametric Method 3 (SE-PM3) will be used. The values of the electronic transfer coefficients of glucose, Cor and insulin with their corresponding amino acids will be calculated. It is expected to determine the interaction between the active sites of insulin and its interaction with glucose and CTS. In conclusion, we hope to verify the theoretical hypothesis that CTS is responsible for hyperglycemia in humans.
Authors and Affiliations
Dr. Manuel González Pérez
Keywords
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