Quantitative reckoning of embelin from fruits of Embelia tsjeriam- cottam using water bath process as an alternate method of extraction
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2015, Vol 3, Issue 3
Abstract
The world is culturally endowed with various forms of healing practices having rich medical wisdom of immense importance. One of such pharmacognostically indispensable medicinal plant is Embelia tsjeriam-cottam A. DC. The active principle of E. tsjeriam-cottam is embelin, possessing a range of pharmacognostic activities including anti-cancer, antioxidant, antiinflammation, antibacterial and analgesic effects. Embelin in fruits of E tsjeriam-cottam was extracted using water bath method. For extraction of embelin from fruits of E. tsjeriamcottam, methanol and chloroform were used as solvents. Fruits were collected from five different agro-climatic zones of Odisha. Comparative estimation of embelin was done through spectrophotometer and High Performance Liquid Chromatographic (HPLC) methods. Samples extracted with chloroform and methanol showed embelin content in a range of 2.13- 0.29% dry wt., and 0.95-0.28% dry wt. respectively using spectrophotometer. In case of HPLC analysis, samples extracted in chloroform and methanol showed embelin content in a range of 1.86-0.27% dry wt., and 0.875-0.26% dry wt. respectively. However the water bath method, used as alternative method for extraction, proved to be less time consuming, costeffective in extracting a pretty good amount of embelin as compared to the conventional (soxhlet) methods of extraction.
Authors and Affiliations
M Mohapatra| Seed Bank & Seed Biology Division, Regional Plant Resource Centre, R & D Institute of Forest and Environment Department, Govt. of Odisha, Bhubaneswar, Odisha, India, U C Basak| Seed Bank & Seed Biology Division, Regional Plant Resource Centre, R & D Institute of Forest and Environment Department, Govt. of Odisha, Bhubaneswar, Odisha, India
Keywords
Related Articles
- EP ID EP15342
- DOI -
- Views 291
- Downloads 13
In-silico designing of NKK: A better ligand than Aciclovir against Herpes Simplex Virus
Aciclovir is the best dr thymidine kinase made by the HSV. In the current study we have successfully designed a drug candidate “NKKâ€, which is far more efficient than aciclovir in terms of binding energy and physioch...
A comparative study on different market samples and standard samples of Shalaparni through physicochemical methods and near infrared spectroscopy
Dashmoolais one of the most important groups explained in Mishrakagana. One of which, Shalaparni is a potent drug used single as well as in various formulations mentioned in classics. Adulteration in Dashmoolaplants is...
Fabrication and Optimization of Novel Lornoxicam Matrix Tablets Using 3-Factor 3- Level Box-Behnken Statistical Design: Invitro and Invivo Evaluation
In the present study efforts have been made to prepare sustained release matrix tablets of Lornoxicam. Matrix tablets were prepared by direct compression method by using Hydroxypropyl methyl cellulose K15 (HPMC- K15),...
Combination of Loperamide and Niacin modify DENA induced altered Liver enzymes
Hepatocellular Carcinoma (HCC) is among the most lethal cancers which makes it the third most frequent cause of cancer related deaths. Diethylnitrosamine (DENA) is a potent initiator and hepatocarcinogen in rats. DENA...
Acute Kidney Injury (AKI) in perinatal asphyxia
Background: Acute kidney injury (AKI) is a common consequence of perinatal asphyxia, occurring in upto 56% of these neonates. It is important to recognize AKI in asphyxiated neonates to facilitate administration of app...