Radio-pathological Factors that Predict the Surgical Outcome of Ossification of Ligamentum flavum of Spine – Series of 31 Cases
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 7
Abstract
Introduction: Ossification of the Ligamentum flavum (OLF) is a pathological condition that affects the ligament and causes slowly progressive myeloradiculopathy in adults. Aim: To study the radiological and pathological factors that are predictive of the surgical outcome of patients with OLF. Materials and Methods: A prospective study of 31 consecutive patients, including 24 men and 7 women with a mean age of 50.45 years, was conducted from 2013 to 2016. Radio-pathological factors included are: Number of segments affected by OLF, Sato’s computed tomography–based classification, and the presence of intramedullary hyper-intensity on T2w magnetic resonance imaging and calcium pyrophosphate dihydrate (CPPD) crystal deposition (pseudogout). All cases underwent decompressive laminectomies. Specimen sent for polarized-light microscopic studies and analyzed for characteristic rod-shaped, birefringent CPPD crystals. Follow up done with a mean duration of 5 months. Recovery rate was calculated with pre-operative and post-operative “Modified Japanese Orthopedic Association” scoring system. Results: Recovery was excellent in 10 cases, good in 6 cases, fair in 12 cases, poor in 3 cases. The author conducted a review of literature in English, Japanese and Korean literature and compared their studies. Conclusion: Early and correct diagnosis is required to avoid poorer results. Long-term follow up needed to determine the factors that predict the surgical outcome. This study also shows how this disease is highly under-reported in India.
Authors and Affiliations
John Christopher, Chockaiah Raja, Heber Anandan
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