Recent advances and future trends in zebrafish bioassays for aquatic ecotoxicology
Journal Title: Ecocycles - Year 2018, Vol 4, Issue 2
Abstract
Zebrafish (Danio rerio), a cyprinid teleost, has become an ideal model species for aquatic ecotoxicology due to the broad spectra of methodologies that have been developed since the 1980s. The zebrafish has many advantages as a model organism e.g. small size, ex utero development of the embryo, short reproductive cycle, and transparent embryos. In addition, the zebrafish shares a high degree of homology with the human genome. It has become a powerful model organism for genetics, development, environmental toxicology, several human diseases and pharmacology. Zebrafish bioassays can be used for environmental monitoring including pollutant evaluations, such as toxic heavy metals, endocrine disruptors, and organic pollutants. The large number of transparent embryos gained from zebrafish females, in vitro and rapid embryonic development and ready-to-use methods of biotechnology enables us to use mostly automatized high-throughput screening not only in pharmaceutical drug development protocols but in aquatic ecotoxicology as well.
Authors and Affiliations
Istvan Magyary
Keywords
Related Articles
- EP ID EP450192
- DOI 10.19040/ecocycles.v4i2.108
- Views 117
- Downloads 0
Role of wastewater treatment plant in environmental cycling of poly- and perfluoroalkyl substances
The role of wastewater treatment plants (WWTP) in environmental cycling of poly- and perfluoroalkyl substances (PFASs) through aqueous effluent, sludge and air emission has been critically reviewed here. Understanding th...
Anthropogenic soils: general aspects and features
In recent decades man's role in soil formation has become a matter of great concern among soil scientists. Man is now considered a soil-forming factor and anthrosolization is recognised as a soil-forming process that con...
Importance of nickel as a nutrient in aquaponic systems - some theoretical considerations
This paper calls the attention to the important role the microelement nickel plays is the decomposition of urea (produced by the fish as waste), and thus to its potential role in aquaponic systems. Since nickel is not in...
Preface to the first issue of Ecocycles
On behalf of the Committee of the European Ecocycles Society (ECyS) we are pleased to announce the publication of the inaugural issue of Ecocycles, our Society’s scientific journal. Ecocycles has been many months in the...
Development of new economies by merging heritage and entrepreneurship
‘Heritage’ could be the driving force in developing new economies in geographic areas with unstable growth. The establishment of industrial remains as heritage during the 1980s and 90s describes a development of heritage...