Recent developments in anticancer applications of the Schiff bases and their metal complexes
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2018, Vol 26, Issue 2
Abstract
Metal complexes of Schiff base signify a class of compounds that have become a field of huge interest for chemists all over the world because of their immense therapeutic applications. They show versatile bonding behaviour because of easy variation in steric and electronic structure of Schiff bases by taking appropriate aldehydes/ ketones and amines. This review highlights the up-to-date research on transition metal complexes of Schiff bases emphasizing mainly on their anticancer applications. We present a complete study of structural factors that are responsible for their activity against particular cancer cell lines and the methods used for such study that includ s both experimental and theoretical approach. Contemporary strategies will be helpful to the development of new drugs based on the moiety and interactions with various cancer cell lines which lead to the apoptosis
Authors and Affiliations
Madhuri Chaurasia, Sulekh Chandra
Keywords
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