Reconstruction of mammalian oocytes by germinal vesicle transfer: A systematic review
Journal Title: International Journal of Reproductive BioMedicine - Year 2017, Vol 15, Issue 10
Abstract
Nuclear transfer procedures have been recently applied for clinical and research targets as a novel assisted reproductive technique and were used for increasing the oocyte activity during its growth and maturation. In this review, we summarized the nuclear transfer technique for germinal vesicle stage oocytes to reconstruct the maturation of them. Our study covered publications between 1966 and August 2017.In result utilized germinal vesicle transfer techniques, fusion, and fertilization survival rate on five different mammalian species are discussed, regarding their potential clinical application. It seems that with a study on this method, there is real hope for effective treatments of old oocytes or oocytes containing mitochondrial problems in the near future.
Authors and Affiliations
Sara Darbandi, Mahsa Darbandi, Hamid Reza Khorram Khorshid, Abolfazl Shirazi, Mohammad Reza Sadeghi, Ashok Agarwal, Safaa Al-Hasani, Mohammad Mehdi Naderi, Ahmet Ayaz
Keywords
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- EP ID EP281275
- DOI 10.29252/ijrm.15.10.2
- Views 84
- Downloads 0
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