Relationship between cerebellar impairments and lexicon retrieval in schizophrenia – preliminary study
Journal Title: Archives of Psychiatry and Psychotherapy - Year 2013, Vol 15, Issue 3
Abstract
Aim of the study. Investigation of relationship between cerebellar motor dysfunctions and language impairments connected with cerebellum during phonological and semantic fluency tasks and verb generation task in schizophrenic patients and healthy control group. Subject or material and methods . 14 schizophrenic patients on olanzapine, clozapine or quetiapine treatment and 13 healthy volunteers were examined. Motor signs were assessed by using the International Co-operative Ataxia Rating Scale (ICARS). Phonological and semantic fluency tasks were performed. All of the words were recorded and counted. Results . Patients with schizophrenia revealed significantly higher ICARS mean score (12.21) than control group (3.92), and lower number of proper generated words in semantic fluency and verb generation tasks. Strong negative correlation (rs(13) = -0.71, p<0.01) was found between ICARS total score and number of proper answers in verb generation task. Discussion . Higher number of total ICARS score in schizophrenia patients in comparison to control group may suggest cerebellar impairments. There is disproportion between semantic and phonological fluency. Significant correlation between verb generation and cerebellar signs supports a hypothesis of cerebellum dysfunction during this task in schizophrenia patients. Conclusions . Schizophrenic patients reveal impairments which may be connected with the cerebellum.
Authors and Affiliations
Adrian Chrobak, Michał Biela, Katarzyna Siuda, Marcin Siwek, Dominika Dudek, Maciej Pilecki
Keywords
Related Articles
- EP ID EP147699
- DOI -
- Views 60
- Downloads 0
Early emotional development and the developmental matrix
The author presents an outline of early emotional development, integrating psychoanalytic theory with studies based on observation. The main conclusions are as follows: (a) Infants are not mere recipients of maternal car...
Psychometric properties of the Polish version of the Body Attitude Test
Background . Polish studies have not been focused on measures which assess attitude toward one’s own body. The purpose of the present study was to develop the Polish version of the Body Attitude Test (BAT) and examine...
Aggression and violence towards health care providers, and effects thereof
Objectives. This study aims to examine the frequency of exposure of health care providers to aggression and violence at work, and the effective factors thereon, as well as the effects of violence on health care providers...
Influence of individual psychological support on the severity of psychopathological symptoms in patients with paranoid schizophrenia
Aim of the studyThe aim of the study was to investigate the relationship between psychological therapeutic interactionsand the severity of psychopathological symptoms in patients diagnosed with paranoid schizophreniaduri...
Thirty years’ follow-up of depressive adolescents: a preliminary report
Aim of the study The purpose of the study was to describe consequences of depression in adolescence. The history of health problems and the choice of life careers, were selected as indicators of the nature of depressive...