Relationship Between Serum Vitamin D Levels and Childhood Recurrent Tonsillitis
Journal Title: Otolaryngology – Open Journal - Year 2017, Vol 3, Issue 1
Abstract
Background: Many factors are associated with the development of recurrent tonsillitis. These include patient incompliance, premature cessation of antibiotherapy, inadequate antibiotic absorbance, bacterial tolerance, bacterial load, bacterial biofilms, and immune system deficiencies. Objective: To compare between recurrent tonsillitis patients undergoing three to seven tonsillitis episodes per year within less than two years with controls having less than three tonsillitis episodes per year on the basis of vitamin D levels. Study design: A retrospective review of clinical charts. Methods: A total of 426 patients were enrolled in this study. The patients were divided into two groups according to the number of acute tonsillitis episodes: Those who had less than three episodes per year (Group A) and those with three to seven episodes per year (Group B). The patients in Group A were assigned to the control group. Each patient in Group B was considered as a potential candidate for recurrent tonsillitis. The total number of episodes of acute tonsillitis within one year, demographic characteristics of the patients and the mean serum 25-hydroxyvitamin D levels of both groups were compared. Results: Group A consisted of 277 patients (132 women, 145 men; mean age 4.40±2.46 years; range 2 to 10 years), while Group B consisted of 149 patients (66 women, 83 men; mean age 5.22±2.26 years; range 2 to 10 years). The mean serum vitamin D levels of Group A and Group B were 57.83±23.10 nmol/L and 48.03±31.36 nmol/L, respectively. Serum vitamin D level of Group B was lower than the Vitamin D levels of Group A which was statistically significant (p=0.001, p<0.01, respectively). Conclusion: This is the first study investigating vitamin D levels among patients for the diagnosis of recurrent tonsillitis during the follow-up. However, further prospective randomized controlled studies are conducted to gain a better understanding as to whether vitamin D supplementation would reduce the tonsillectomy rates in the diagnosis of recurrent tonsillitis.
Authors and Affiliations
Mustafa Çelik
Keywords
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- EP ID EP546199
- DOI 10.17140/OTLOJ-3-135
- Views 131
- Downloads 0
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