Relationship of Gestational Diabetes Mellitus with Hypothyroidism in Pregnancy
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 7
Abstract
The objective is to study if there is a relationship between gestational diabetes mellitus with hypothyroidism in pregnancy. Between June 2014 and May 2015, serum thyrotropin (TSH) screening was performed on all women who presented for prenatal care. Women identified with elevated thyrotropin level were considered hypothyroid. Out of these 100 women were randomly selected and subjected to oral glucose tolerance test with 75gm oral glucose according to DIPSI guidelines. Along with the hypothyroid cases 100 pregnant women with normal Serum TSH level were also subjected to the oral glucose tolerance test which would act as the control group for the analysis. For this analysis normal thyrotropin values were taken as 0.2 to 3mIU/L as per American Thyroid Association guidelines. The incidence of gestational diabetes mellitus was compared between the study and the control group. Of the 200 women included in the study 100 were euthyroid, 100 were hypothyroid. Gestational diabetes was more in the hypothyroid group (8%) than in the control group (1%).( P=0.0349). The risk of developing gestational diabetes increases with hypothyroidism. This supports a relationship between hypothyroidism and diabetes, diagnosed during pregnancy. Keywords: GDM(Gestational diabetes mellitus), hypothyroidism, DIPSI(Diabetes In Pregnancy Study Group India), OGTT(Oral Glucose Tolerance Test), TSH(Thyroid Stimulating Hormone), DGGT (Decreased Gestational Glucose Tolerance ).
Authors and Affiliations
Das Bishnu Prasad, Deka Nabanita, Baishya Swagata
Keywords
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