RELIABILITY AND VALIDITY OF HYPOTHETICAL SCENARIOS FOR ESTIMATING WILLINGNESS TO PAY (WTP) PER QUALITY ADJUSTED LIFE YEAR (QALY) IN INDONESIA SETTING
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2017, Vol 9, Issue 12
Abstract
Objective: To estimate validity and reliability of WTP questionnaire which WTP value can be taken as an indication of the monetary value of health gains, which may carry information regarding the appropriate height of the cost-effectiveness threshold.Methods: Three hundred respondents, in Yogyakarta province, Indonesia, were interviewed during June 2017. We examine a value of WTP associated with the following scenarios: 1) improving moderate condition; 2) extending life during terminal illness, and 3) lifesaving. The interview ascertained maximum hypothetical WTP for one QALY using a dichotomous bidding format with an open-ended final question, along with questions about the socio-economic factors. Concerning validity, the WTP of the 3 versions of hypothetical scenarios were compared as known-group validity and analysis of the sensitivity and specificity was performed. Test-retest reliability and alpha Cronbach were employed to measure internal consistency.Results: Analysis generally confirmed the validity and reliability of the WTP hypothetical scenarios. In terms of known group validity, there was significant difference across two scenarios (treatment v. s lifesaving), but no significant difference between mean WTP for treatment and terminal illness was found. Mean WTP for terminal illness (38 Million IDR) and lifesaving scenario (16 Million IDR) was significantly higher than that of treatment scenario (14 Million IDR). The WTP instrument showed good convergent validity (r=0.784), when comparing correlation between WTP value and utility score. Estimation of scenario’s sensitivity and specificity in deriving expected WTP were 70.33 % and 38.98 %, respectively. The positive and negative predictive values were 64 % and 46 %. The test-retest reliability of WTP values indices excellent stability and reliability of the instrument with Spearman’s rank correlation coefficient of 0.816 (p<0.001)Conclusion: This study demonstrated that the WTP instrument is feasible and relatively reliable for measuring the WTP values in Indonesia. For wider application of the instrument, its validity should be investigated further. Meanwhile, adoption of WTP as an empirical evidence of societal values is encouraged.Â
Authors and Affiliations
Susi Ari Kristina, Dwi Endarti, Tri Murti Andayani, M. Rifqi Rokhman
Keywords
Related Articles
- EP ID EP575435
- DOI 10.22159/ijpps.2017v9i12.22657
- Views 82
- Downloads 0
ANTIMALARIAL ACTIVITY AND CYTOTOXICITY STUDY OF ETHANOL EXTRACT AND FRACTION FROM ALECTRYON SERRATUS LEAVES
Objective: The resistance of Plasmodium falciparum to standard antimalarial drugs has led the scientist to investigate medicinal plants as new potentials in the treatment or prevention of malaria. Previous study showed t...
FAST CHIRAL HPLC PROCEDURE FOR THE SIMULTANEOUS DETERMINATION OF DROPROPIZINE ENANTIOMERS AND ITS NONPOLAR IMPURITY IN RAW MATERIAL AND PHARMACEUTICAL FORMULATION
Objective: Levodropropizine is a novel antitussive drug, which occurs as enantiomers. They are levodropropizine (2S) [LDP] and dextrodropropizine (impurity A) (2R) [DDP]. An isocratic chiral high performance liquid chrom...
CURCUMIN ATTENUATES LEAD (Pb)–INDUCED NEUROBEHAVIORL AND NEUROBIOCHEMICAL DYSFUNCTION: A REVIEW
Lead is one of the common chemical elements that is assigned the symbol Pb which came from the Latin Plumbum. Pb is widely used in the field of coating, refine and glaze ceramics and pottery. It is still used in the prod...
STUDY ON VARIATIONS IN THE BRANCHING PATTERN OF ARCH OF AORTA
The most common branching pattern of the aortic arch in humans comprises of three great vessels, during the routine dissection for 1st MBBS we encountered variations in the branches of arch of aorta, so the study was con...
PHYTOCHEMICAL INVESTIGATION OF FRUIT EXTRACT OF ELAEOCARPUS GANITRUS
Objective: The present study aimed to investigate the qualitative and quantitative phytochemical analysis of ethanolic fruit extract of medicinally important plant of Elaeocarpus ganitrus for identification of major bioa...