RENAL COMPLICATIONS IN HIV PATIENTS IN AND AROUND MADURAI- A CROSS-SECTIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 74
Abstract
BACKGROUND HIV is the modern pandemic spreading throughout the world in a rampant manner. The renal manifestations of HIV infection occurs commonly during all stages of infection [Medical management of AIDS- Merle A Sande et al, Renal Manifestations of HIV infection occurs in 6% - 10% of HIV seropositive individuals] [Kidney Int 44:1327-1340, 1993; AmJ Kidney Dis 26: 446-453, 1995]. Fluid, electrolytes and acid-base abnormalities as well as acute renal failure have been observed frequently, mainly as a consequence of drug toxicity or opportunistic infections [Medical Management of AIDS- Merle A. Sande]. The objectives of this study are1. To find out prevalence of renal failure among HIV patients admitted to tertiary care hospital. 2. To find out the spectrum of renal manifestations in HIV positive patients hospitalised at STD ward. MATERIALS AND METHODS It is a cross-sectional study. The study was conducted in HIV positive patients who were admitted in STD ward, Government Rajaji Hospital, Madurai during the period from 01-02-2002 to 31-01-2004 (2 years). The total number of inpatients are 360, of which 30 are fit to be included in the study. The criteria for including in the study are significant proteinuria, elevated serum creatinine of more than 1.5 mg/dL or presence of both. RESULTS 360 HIV patients were admitted during the study period and 30 were found fit for the study, i.e. out of 360 HIV patients, 8.33% suffered from renal involvement. In our study, 30 – 39 age group constituted 50% and males are affected more than females. CONCLUSION HIV is a common problem in our clinical practice. Renal involvement in HIV patients carries poor prognosis. The most common age group affected are 20 - 45 years. Males seek the medical help more often than females and this could be the reason for male predominance in our study. So it is important to detect all cases early and treat effectively to improve the quality of life.
Authors and Affiliations
Balasubramanian Narayana Srinivasan, Pravin A. J. S.
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