Renal-limited lupus-like glomerulonephritis
Journal Title: Archives of Renal Diseases and Management - Year 2017, Vol 3, Issue 2
Abstract
In the setting of an IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological findings that strongly suggest the diagnosis of lupus nephritis (LN) including “full-house” immunofluorescence staining for IgG, IgM, IgA, C3 and C1, extraglomerular immune deposits, combined mesangial, subendothelial and subepithelial immune deposits and the presence of endothelial tubuloreticular inclusions (TRI). If at the time of biopsy or during the period of follow-up, the patient displayed no extrarenal manifestations or serological evidence of systemic lupus erythematosus (SLE) it is denominate renal-limited lupus-like glomerulonephritis (RLLN) and there are reports both adults and children. Purpose of the study: Clinical features review of in the peer-reviewed academic literature.
Authors and Affiliations
Martín Noemi Esparza, Rodríguez Rita Guerra, Tagarro Ernesto Fernández, González Santiago Suria, Cantón César García
Renal-limited lupus-like glomerulonephritis
In the setting of an IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological findings that strongly suggest the diagnosis of lupus nephritis (LN) including “full-house” immunofluorescence...
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