Renoprotection and its association with eGFR and renal functional reserve
Journal Title: Нирки - Year 2018, Vol 7, Issue 4
Abstract
Renoprotection is a system of measures for primarily pharmacological control, contributing to the continued preservation of renal function. When choosing renoprotection tactics, it is necessary to consider not only the estimated GFR (using the EPI formula), but also a functional renal reserve. The method of determining the renal reserve with oral administration of 0.45–0.50% sodium chloride solution at the rate of 0.5 % of body weight is considered to be physiologically substantiated. The renal reserve determining based on this technique as a routine method for examining nephrological patients provides additional information not only on the number of functioning nephrons, but also on their condition. A differentiated approach to prescribing renoprotective agents has been proposed, taking into account the stage of the disease and the functional renal reserve for maximum preservation of functioning nephrons.
Authors and Affiliations
D. D. Ivanov, A. I. Gozhenko, L. N. Savitskaya
Keywords
Related Articles
- EP ID EP421431
- DOI 10.22141/2307-1257.7.4.2018.148512
- Views 84
- Downloads 0
Evaluating the Effectiveness of the Treatment for Inflammatory Disorders of Male Genital Organs of Trichomonal Bacterial Origin Using Grandazol
The article presents the results of studying clinical and microbiological efficacy of Grandazol in the comprehensive treatment for inflammatory disorders of male genital organs of trichomonal bacterial origin.
Hypoxia-inducible factor for the treatment of anemia in chronic kidney disease
Studies in the field of oxygen-dependent regulation of erythropoiesis provided new data on the pathogenesis of anemia associated with chronic kidney disease, which led to the development of therapeutic agents for treatme...
Executive summary of the 2018 KDIGO Hepatitis C in CKD Guideline: welcoming advances in evaluation and management
.
Chronic kidney disease and anemia: application of ferrous bisglycinate chelate for correction of iron deficiency in patients with chronic kidney disease
Anemia is a component of chronic kidney disease, having erythropoietin- and iron deficiency nature. 2012 KDIGO guidelines determine anemia as a hemoglobin concentration < 120 g/l in women and < 130 g/l in men. An iron de...
Kidney Transplantation from АВ0-Incompatible Living Family Donor
The introduction into the clinical practice of kidney transplantation from АВ0-incompatible living donor may be one of the ways to solve the problem of shortage of cadaveric donor organs. The objective of this study was...