Repolarization Parameters in Patients with Premature Coronary Artery Disease
Journal Title: Çocuk Acil ve Çocuk Yoğun Bakım Dergisi - Year 2019, Vol 72, Issue 1
Abstract
Objectives: Coronary artery disease (CAD) in young adults is relatively rare. Few data on CAD in young adults are available in the literature. In the current study, repolarization parameters were evaluated in patients with newly diagnosed premature CAD. Materials and Methods: A total of 200 patients [128 male, 38.0 (29.3-42.0) years] were included and 100 cases with newly diagnosed premature coronary heart disease (aged ≤45 years) formed the study group. Remaining 100 cases were well-matched controls. Repolarization parameters including QTc interval, Tp-e interval and Tp-e∕QTc in leads DII, V2 and V6 were compared between the two groups. Results: The median QTc interval (430.3 ms vs 405.3 ms, p<0.001) in lead D2, (433.8 ms vs 404.7 ms, p<0.001) in lead V2 and (430.2 ms vs 401.7 ms, p<0.001) in lead V6; the median Tp-e interval (80 ms vs 64 ms, p<0.001) in lead D2, (82 ms vs 74 ms, p<0.001) in lead V2 and (88 ms vs 72 ms, p<0.001) in lead V6; and the median Tp-e/QTc (0.188 vs 0.158, p<0.001) in lead D2, (0.190 vs 0.181, p=0.022) in lead V2 and (0.196 vs 0.183, p<0.001) in lead V6 were significantly higher in patients with premature CAD compared controls, respectively. Conclusion: In conclusion, premature coronary heart disease may be related to abnormal dispersion of repolarization and subsequent arrhythmic risk.
Authors and Affiliations
Firdevs Ayşenur Ekizler, Bahar Tekin Tak, Serkan Çay, Habibe Kafes, Özcan Özeke, Fırat Özcan, Dursun Aras
Keywords
Related Articles
- EP ID EP670504
- DOI 10.4274/atfm.galenos.2019.63935
- Views 129
- Downloads 0
Repolarization Parameters in Patients with Premature Coronary Artery Disease
Objectives: Coronary artery disease (CAD) in young adults is relatively rare. Few data on CAD in young adults are available in the literature. In the current study, repolarization parameters were evaluated in patients wi...
Severe Methemoglobinemia Due to Nitrite Intoxication in a Child Who was Misdiagnosed with Sepsis
We present here, a child with an extremely high methemoglobin level caused by inadvertently prepared sodium nitrite and potassium nitrite by a pharmacist. On physical examination, he had tachycardia and tachypnea. He had...
Retrospective Analysis of Poisoning Cases Our Followed in Pediatric Intensive Care Unit
Introduction: Although poisonings represent a significant number of preventable causes of morbidity and mortality admissions to hospital and pediatric intensive care unit, data about poisonings requiring pediatric intens...
Methemoglobinemia Associated with Prilocaine Use in Circumcision
Methemoglobinemia (MetHb) occurs when the ferric iron with the valence of +2 contained in hemoglobin becomes +3 ferric iron due to various exogenous and endogenous reasons. MetHb shifts the oxygen dissociation curve to t...
Animal Bites Cases Presented to a University Hospital Pediatric Emergency
Introduction: Rabies is still one of the important public health problems both in the world and in our country. The highest risk of rabies comes from contact with pets, especially dogs. The aim of this study was to evalu...