Repolarization Parameters in Patients with Premature Coronary Artery Disease
Journal Title: Çocuk Acil ve Çocuk Yoğun Bakım Dergisi - Year 2019, Vol 72, Issue 1
Abstract
Objectives: Coronary artery disease (CAD) in young adults is relatively rare. Few data on CAD in young adults are available in the literature. In the current study, repolarization parameters were evaluated in patients with newly diagnosed premature CAD. Materials and Methods: A total of 200 patients [128 male, 38.0 (29.3-42.0) years] were included and 100 cases with newly diagnosed premature coronary heart disease (aged ≤45 years) formed the study group. Remaining 100 cases were well-matched controls. Repolarization parameters including QTc interval, Tp-e interval and Tp-e∕QTc in leads DII, V2 and V6 were compared between the two groups. Results: The median QTc interval (430.3 ms vs 405.3 ms, p<0.001) in lead D2, (433.8 ms vs 404.7 ms, p<0.001) in lead V2 and (430.2 ms vs 401.7 ms, p<0.001) in lead V6; the median Tp-e interval (80 ms vs 64 ms, p<0.001) in lead D2, (82 ms vs 74 ms, p<0.001) in lead V2 and (88 ms vs 72 ms, p<0.001) in lead V6; and the median Tp-e/QTc (0.188 vs 0.158, p<0.001) in lead D2, (0.190 vs 0.181, p=0.022) in lead V2 and (0.196 vs 0.183, p<0.001) in lead V6 were significantly higher in patients with premature CAD compared controls, respectively. Conclusion: In conclusion, premature coronary heart disease may be related to abnormal dispersion of repolarization and subsequent arrhythmic risk.
Authors and Affiliations
Firdevs Ayşenur Ekizler, Bahar Tekin Tak, Serkan Çay, Habibe Kafes, Özcan Özeke, Fırat Özcan, Dursun Aras
Keywords
Related Articles
- EP ID EP670504
- DOI 10.4274/atfm.galenos.2019.63935
- Views 127
- Downloads 0
The Cortico-hippocampal Circuit: The Brain’s Center for Mapping and Declarative Memory
Perceived stimuli from the external world are relayed to various association cortices after they reach their respective primary cortices. Information to be encoded as long-term memory is relayed to the dentate gyrus via...
Cerebral Salt-Wasting Syndrome in a Patient with Subacute Sclerosing Panencephalitis: The Use of Fludrocortisone in Treatment
Cerebral salt wasting syndrome (CSWS) is characterized by natriuresis and associated with hypovolemia, and hyponatremia. The underlying pathogenesis is not clearly known. It is often confused with syndrome of inappropria...
Clinical Features of 2017-2018 Seasonal Influenza Infection: A Single-Center Experience
Introduction: Influenza is a serious infectious disease causing mortality and morbidity. The aim of our study was to describe the incidence, seasonal distribution and clinical characteristics of influenza cases in 2017-2...
Characteristics of Children Admitted to the Emergency Department with Convulsive Epileptic Seizures: A Single-Center Study
Introduction: To evaluate the etiology and characteristics of children admitted to the emergency department with an acute convulsive epileptic seizure. Methods: Data of patients who were admitted to the emergency departm...
Use of Ketamine Infusion and Azithromycin as an Adjunct Therapy in Severe Acute Bronchiolitis
.