Resealed Erythrocytes as a Carrier for Drug Targeting: A Review
Journal Title: The Pharma Innovation - Year 2012, Vol 1, Issue 2
Abstract
Erythrocytes have been the most interesting carrier and have found to possess great potential in drug targeting. Resealed erythrocytes are gaining more popularity because of their ability to circulate throughout the body, biocompatibility, zero order release kinetics, reproducibility and ease of preparation. Most of the resealed erythrocytes used as drug carriers are rapidly taken up from blood by macrophages of reticuloendothelial system (RES), which is present in liver, lung, and spleen of the body. The aim of the present review is to focus on the various features, drug loading technology and biomedical application of resealed erythrocytes.
Authors and Affiliations
Ashok Kumar, Mansi Verma, K. K. Jha
Recent Trends in Medicinal Uses and Health Benefits of Indian Traditional Herbs Aegle Marmelos
Nature produces several food items for every season. Their use in that particular season proves to be highly beneficial for our body and the entire state of health. Bael fruit is one such blessing from nature for the man...
Method Development and Validation of Neverapine by Rp-Hplc
A simple and accurate RP-HPLC method has been developed for the estimation of Neverapine in bulk and pharmaceutical dosage forms, using C-18 column 150 x 4.6 mm i.d, 5μm particle size in isocratic mode, with mobile phase...
A Review Article on Colonic Targeted Drug Delivery System
Colon targeted drug delivery system (CTDDS) delivered as both local and systemic delivery of drugs. Local delivery could, for example, allow topical treatment of inflammatory bowel disease (IBD). Treatment could be enhan...
A Comprehensive Review of Pulsatile Drug Delivery System
Novel Oral Drug Delivery technologies have emerged and expanded into different drug delivery system with different drug release mechanisms.Sophisticated instrumentation,modern mathematical models and computation power h...
RP-HPLC Method Devlopment and Validation of Domperidone in Solid Dosage Form
A simple, accurate, reliable and reproducible HPLC method was developed for the determination of Domperidone (DOM) in solid dosage forms. The method employed C18 column, water: methanol (55:45) as mobile phase and detect...