Research progress on bipolar disorder and pregnancy complications and neonatal risk.
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 1
Abstract
Pregnant women with bipolar disorder (BD) are a high-risk pregnancy state. Necessary psychotropic drug treatment, special stress reactions, bad living habits, and fluctuations in pregnancy hormones all increase the risk of pregnancy to a certain extent. Risks of complications such as hypertension, gestational diabetes, premature birth and spontaneous abortion. Drugs can penetrate the placental blood-brain barrier and enter the maternal-fetal microcirculation. Combined with the effects of genetic genes and the environment, they can induce neurodevelopmental abnormalities in the fetus, leading to congenital malformations, attention deficit hyperactivity disorder, autism spectrum disorder and other diseases after birth. The mode of delivery may also be affected. Women with BD often give birth by caesarean section. It is particularly important to weigh the choice of drug types and dosages, which will help improve the accuracy of clinical risk management and disease control of pregnancy-related mental disorders.
Authors and Affiliations
Yulin ZHANG, Xiaoling FENG
Keywords
Related Articles
- EP ID EP750405
- DOI 10.3969/j.issn.1002-0152.2024.01.011
- Views 34
- Downloads 0
A case of spinocerebellar ataxia type 8 presenting with multiple system atrophy cerebral type
We report a case of spinocerebellar ataxia type 8 (SCA8) presenting with multisystem atrophic phenotype. The patient was a 57-year-old male with a 4-year course of illness with dizziness and ataxia as the first symptoms,...
A case of propriospinal myoclonus with typical axial convulsions during sleep
Propriospinal myoclonus (PSM) is a rare painless movement disorder characterized by recurrent axial myoclonus during the wake and sleep transition periods. The recurrent muscle twitches during the hypnotic period severel...
Study on the mechanism of losartan reducing the risk of comorbid depression in epileptic rats
[Objective] To investigate the effectiveness and mechanisms of losartan in improving comorbid depression in epileptic rats. [Methods] Male rats were randomly divided into three groups: The losartan-pilocarpine group (PL-...
Research progress on the study of aceruloplasminemia
Aceruloplasminemia (ACP) is a rare, adult-onset autosomal recessive disorder characterized by ceruloplasmin (CP) deficiency and iron metabolism disorders, with typical clinical manifestations of the triad of "neurologica...
Establishment of stable Schwann cell lines with genetic intervention of MST2 and its appliance in the detection of mitochondrial membrane potential
[Objective] To construct rat Schwann cell RSC96 cell lines that stably knock down or overexpress mammalian ste20-like kinase 2 (MST2), and preliminarily explore its regulatory effect on mitochondrial membrane potential....