Research progress on ketamine for the treatment of substance use disorders
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 10
Abstract
Substance use disorder is a complex health condition characterized by excessive dependence and abuse of psychoactive substances. Current treatments are few and generally ineffective, and new treatment methods are urgently needed. In recent years, ketamine has been found to be effective in the treatment of substance use disorders in controlling relapse rates and reducing withdrawal reactions in clinical studies. Basic research has shown that ketamine has a therapeutic effect by altering neuroplasticity and modulating neurofunctional networks. However, the use of ketamine may lead to side effects such as increased blood pressure and psychiatric symptoms, and potential addiction. But current clinical studies are optimistic about its safety. As a fast-acting drug with a novel mechanism of action, ketamine needs to be studied in depth to explore its benefits and risks, thereby providing a safe and effective new method for the treatment of substance use disorders.
Authors and Affiliations
Tinghan FU, Huanzhong LIU, Kai. ZHANG
Keywords
Related Articles
- EP ID EP759181
- DOI 10.3969/j.issn.1002-0152.2024.10.011
- Views 31
- Downloads 0
Application of free fascia lata for dura mater reconstruction in the treatment of the refractory intracranial infection after craniotomy
[Objective] To summarize the application of free fascia lata in reconstructive surgery for patients with refractory intracranial infection after craniotomy. [Methods] A retrospective analysis was performed for the clinic...
Fibrocartilage embolic spinal cord infarction with intervertebral disc-herniation: Two case report
The clinical features, imaging data and prognosis of 2 patients with spinal cord infarction were summarized. Both patients presented with acute onset paraplegia and urinary retention. Spinal MRI showed high T2 signal and...
A study on the correlation between childhood trauma, resilience and non-suicidal self-injury in adolescents
[Objective] To explore association between childhood trauma, resilience and non-suicidal self-injury in adolescents. [Methods] One hundred and fifty-eight first-episode adolescent patients with mood disorders were select...
Clinical characteristics of late-life depression patients with venous thromboembolism in the elderly ward
[Objective] To analyze the clinical characteristics and related to risk factors of late-life depression patients with venous thromboembolism in the elderly ward. [Methods] A retrospective analysis was conducted on 143 ho...
Light and challenges: Advances in targeted therapy for glioma
Glioma is the most common malignant primary brain tumor in adults, characterized by rapid malignant progression, high recurrence rates, and high mortality. The main treatment methods are surgery followed by radiotherapy...