Research progress on the pathogenesis of microvascular neuropathy in diabetic retinopathy
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 5
Abstract
Diabetic retinopathy is one of the common and serious microvascular complications of diabetes. In foreign countries, DR is the leading cause of blindness in the working age group(20-64 years). In China, the incidence of DR and the rate of blindness increase year by year, which seriously affects the patients' quality of life. Previous studies on the pathogenesis and treatment of diabetic retinopathy were mainly focused on the microvascular; in recent years, with the deepening of researches, more and more scholars believe that DR is no longer simply a kind of microangiopathy, but is also accompanied by retinal neurodegeneration. However, studies on the pathogenesis of microvascular disease and neurodegenerative changes of diabetic retinopathy in the literature domestic and abroad are mostly single. This article reviews the relationship between microvascular disease and neurodegenerative changes in diabetic retinopathy.
Authors and Affiliations
Tian - Hua Piao
Intravitreal injection of Ranibizumab combined with retinal photocoagulation for CRVO with retinal neovascularization and macular edema
AIM: To investigate the clinical efficacy of intravitreal injection of Ranibizumab combined with retinal photocoagulation(523 laser)in the treatment of central retinal vein occlusion(CRVO)with retinal neovascularization...
Secondary intraocular hypertension after vitrectomy in patients with proliferative diabetic retinopathy
AIM: To study the postoperative incidence and related factors of high intraocular pressure after vitrectomy in patients with proliferative diabetic retinopathy(PDR). <p>METHODS: Selected in February 2014 to February 2016...
Effect of intravitreal injection of anti-VEGF on choroidal thickness and blood flow in posterior ciliary artery in patients with wet ARMD
AIM:To investigate the effect of intravitreal injection of anti-vascular endothelial growth factor(VEGF)on choroidal thickness and posterior ciliary artery blood flow in patients with wet age-related macular degeneration...
Research advances of endoplasmic reticulum stress in high glucose environment and its related ophthalmic diseases
Endoplasmic reticulum(ER)is a place where it folds and synthesizes the proteins. ER stress was induced when a variety of physiological and pathological factors happened, under which the protein misfolding occurred, the u...
Research on correlation between diabetic retinopathy and dry eye
AIM:To research the correlation between dry eye and diabetic retinopathy(DR)in type 2 diabetes mellitus patients. <p>METHODS:A total of 150 patients with type 2 diabetes mellitus collected from August 2015 to February 20...