Reserve capacity of remaining kidney function after livingrelated donor unilateral nephrectomy
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 2
Abstract
Objective: To investigate early postoperative renal function changes and its influence factors after living-related donor unilaterl nephrectomy. Method: 109 cases of living-related kidney donors were enrolled in this study. Estimated glomerular filtration rate (eGFR) was calculated using the abbreviated Modification of Diet in Renal Disease (aMDRD) formulae. Emission computed tomography (ECT) equipment was applied to detect the GFR of both kidneys and GFR of each kidney before nephrectomy was estimated in proportion. Observe eGFR changes and compensatory rate of the retained kidney in the first month after donor nephrectomy and at the same time observe the influence factors,eg, gender, age, body mass index (BMI) and preoperative GFR. Results: The eGFR of the retained kidney increased gradually and reached a peak at 4 days after nephrectomy. The average eGFR increased from 70.60 ml/min before nephrectomy to 88.15 ml/min at the endpoint with the average compensatory rate 24.86%. The eGFR of the male group and the female group increased with the compensatory rate 22.89 % and 24.69%. For donors over 50 years and doners less than 50 years old, the eGFR increased with compensatory rate 13.81% and 28.21%. For doners BMI above 23.0 kg/m2 and below 23.0 kg/m2 the average eGFR increased with the compensatory rate 25.56% and 25.46%. For doners GFR above 60 ml/min and below 60 ml/min before surgery, the average eGFR increased with the compensatory rate 16.44 % and 35.79%. Conclusion: The eGFR of the retained kidney increased significantly after unilateral nephrectomy. Gender, age and preoperative GFR produced significant impact on the renal recovery of the retained kidney after nephrectomy
Authors and Affiliations
Ji Shu- ming, Li xue, Wen Ji- qiu, Cheng Dong-rui, Chen Jin-song
Keywords
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