Response of Overweight Patients with Oligozoospermia to Coenzyme Q10 Treatment
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 2
Abstract
Background: Sperm Concentration Could Be Affected By Many Factors And Body Weight May Be One Of These Factors ,So To Increase Sperm Concentration In Overweight Patients With Oligozoospermia; Agents With Effects On Both Body Weight And Sperm Concentration May Produce Good Response. Objectives: To Assess The Effects Of Coenzyme Q10 On The Increased Body Weight And Sperm Concentration In Patients With Oligozoospermia . Patients And Methods: Study Was Carried Out From March 2011 To September 2012 In Which 60patients With Idiopathic Oligozoospermia Were Randomly Assigned 200mg Coq10 Soft Gel Capsule Once Daily, For Six Months. Standard Seminal Fluid Analysis Was Carried Every Month. Body Mass Index Was (BMI) Evaluated At Baseline And After 6months . Only 52 Patients Completed The Six Months Trial. Results: There Was A Progressive And Significant Improvement In Sperm Concentration (21.42±9.57 Vs 11.12±4.59 At Baseline, P=<0.001). Also There Was A Significant Decrease In BMI After 6 Months As Compared With Baseline Data (From 28.06±6.06 To 25.76±6.06, P < 0.005) And There Was A Significant (P<0.05) Negative Correlation Between BMI And Sperm Concentration For All Patients At Baseline And After 6 Months. Conclusion: There Is A Correlation Between Body Weight And Sperm Concentration And Co Enzyme Q10 Has Effects On Both Body Mass Index And Sperm Concentration.
Authors and Affiliations
Huda I. Al-Qadhi, Haidar M. Jawad, Usama S. Al-Nasiri 3
Keywords
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- EP ID EP383505
- DOI 10.9790/3008-1102026368
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