RESPONSE TO LAPAROSCOPIC SPLENECTOMY IN PATIENTS WITH IMMUNE THROMBOCYTOPENIC PURPURA: EVALUATION OF SINGLE CENTER DATA
Journal Title: Dokuz Eylul Universitesi Tip Fakultesi Dergisi - Year 2019, Vol 33, Issue 2
Abstract
Objective: Immune thrombocytopenic purpura (ITP) is one of the most common causes of acquired thrombocytopenia. Laparoscopic splenectomy (LS) is widely applied in the second line treatment of patients with ITP. The aim of this study is to evaluate the peri-operative and long-term results of patients with ITP, who underwent LS, according to Vicenza consensus criteria.Material and Method: The demographic and operative data, morbidity, mortality and treatment responses of the patients with ITP, who underwent LS in our center, between 2010 and 2017 were analyzed retrospectively from prospectively collected databaseResults: Thirty-eight patients (14 male - 24 female) were included in the study. The mean age of the patients was 38.89±16.13 (18-70). The mean operation duration was 71.57±20.43 (45-135) minutes. The mean bleeding amount during surgery was 43.28±49.21 (10-250) cc. No peri-operative mortality was observed in any of the patients. Minor morbidity was observed in three patients (7.8%). The mean hospital stay was 4.2±1.3 (2-7) days. According to Vicenza consensus criteria, 25 patients (73.5%) had complete response, two patients (5.3%) had response, four patients (11.8%) were evaluated as non-responsive and 3 patients (8.8%) had loss of response. No significant relationship was identified between the age of the patients and their response to splenectomy (p = 0.43). The mean follow-up period was 38.15 ± 25.24 months (6.53 - 88.57). Conclusion: Laparoscopic splenectomy can be applied with low morbidity and mortality in the second line treatment of patients with ITP.
Authors and Affiliations
Cihan Ağalar, Aybüke Olgun, Mücahit Özbilgin, Koray Atila, Ali Durubey Çevlik, Serhan Derici, Özden Pişkin, Sermin Özkal, Tufan Egeli, Tarkan Ünek
Keywords
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- EP ID EP637868
- DOI 10.5505/deutfd.2019.67590
- Views 108
- Downloads 0
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