Retrospective Analysis of Clinical Isolates of Mycobacterium Tuberculosis in a Tertiary Centre in Kerala: Two Year Study
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 5
Abstract
Tuberculosis is a major public health problem in India which accounts for one fifth of the global burden. It is estimated that about 40% of the Indian population is infected with tubercle bacilli. Automated methods and molecular methods are new developments in the diagnostic field of mycobacteria. But culture is the gold standard for diagnosis. A retrospective analysis of the culture positives obtained by conventional culture method using solid medium Lowenstein Jensen medium for 2 years from January 2015 to December 2016 by processing various clinical specimens collected and sent to the Mycobacteriology laboratory in the Dept. of Microbiology at Govt. Medical College, Thiruvananthapuram, Kerala was done. Among 548 samples received 16 samples yielded Mycobacterium Tuberculosis. Culture positivity was 4.28% smear positive for acid fast bacilli after Ziehl Neelsen staining was 3.83%. Total number of patients and culture positivity were more in males than in females. Since the facility for sensitivity testing is not available all the culture positive cases were referred to RNTCP for treatment and periodic assessment. Mortality rate was 6.25% among the culture positive cases.
Authors and Affiliations
Dr. Lancy. J
Keywords
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