Retrospective Analysis of Patients with Sternum AsA Site of Recurrence in Treated Cases of Carcinoma Breast and Effect of Palliative Therapy-ASingle Cancer Centre Experience.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Background: Bone metastasis is a frequent complication of cancer. It occurs in up to 70% of patients with advanced breast cancer. Sternal involvement in patients with breast cancer is relatively rare and its treatment is still controversial. The present retrospective analysis aims to bring forth the role of palliative treatment (radiotherapy and chemotherapy) in this unusual site of bony recurrence. Material & methods: Data of pre-treated carcinoma breast patients from Nov 2012- Nov 2013 who had histopathologically proven sternal site recurrence and had received palliative treatment (radiotherapy & chemotherapy) were considered for analysis. Response to palliative radiotherapy and chemotherapy was assessed using RECIST criteria version 1.1, whilepain was assessed using pre and post treatment VAS score. Result: 9 patients with sternum as site of metastasis were detected. Post RT 7/9 (77.77%) patients had partial response while 2/9 (22.22%) patient had negligible response. 2/9 (22.22%) patients after completion of palliative radiation and chemotherapy treatment had complete response,6/9 (66.66%) had partial response and 1 had stable disease. All 9 patients were found to be having moderate response to pain, assessed 1 month after completion of treatment. Conclusion: Sternal metastasis to a certain extent can be taken care of with the palliative treatment and supportive care but the exact etiopathogenesis, prevention protocols and definitive modality of treatment still needs to be explored and discussed.
Authors and Affiliations
Divyesh Kumar
Keywords
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- EP ID EP590900
- DOI 10.9790/0853-1601108287.
- Views 41
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