Retrospective Study on Consanguineous Marriage Birth Deffects Among Patients Attending Pediatric Ward In Tertiary Care Hospital, South India
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Consanguinity is the quality of being descended from the same ancestor as another person. Consanguinity is prevalent in many middle eastern and Arab cultures and societies. Genetic disorders and congenital abnormalities occur in about 2%-5% of all live births, account for up to 30% of paediatric hospital admissions and cause about 50% of childhood deaths in industrialised countries. To determine the prevalence of consanguineous marriages, type of consanguinity and to determine the role of consanguinity on congenital malformations so as to create awareness. Retrospective hospital based study with consecutive sampling of 1552 babies in Mahatma Gandhi Memorial Hospital over a period of 12 months from January to December 2015.Out of 1552 babies 61 babies were having congenital malformations. Malformed babies were noted in 8 % of consanguineous marriages versus 1 % in non-consanguineous marriages, with P value of 0.04 which is statistically significant. In conclusion, congenital malformations are more in consanguineous marriages i.e., consanguinity may play important role in high rates of malformations in children. In order to prevent, genetic counselling before marriage must be applied for all couples because they may have family history of genetic disorders and especially consanguineous couples.
Authors and Affiliations
Balram B, Sudhakar Ajmeera, Amrutha Keerthi Pogula, Divya Mitukula, Nagesh Adla
Keywords
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- EP ID EP409160
- DOI 10.9790/0853-1711020811.
- Views 92
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