Review of treatment outcome of multi-drug resistant tuberculosis
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 3
Abstract
Introduction Multidrug resistant tuberculosis MDR TB is essentially a manmade phenomenon and arises mainly due to inadequate treatment of drugsensitive TB Drug resistance is seen in 13 of new cases and 12 of retreated tuberculosisMaterial and Methods We studied 291 cases of multidrug resistant tuberculosis registered at drug resistant tuberculosis DRTB center Mysore Patients were treated according to programmatic management of drug resistant tuberculosis PMDT guidelines by DRTB committee of the hospitalResults Out of 291 treated cases of MDR TB 41 were diagnosed when they were on Category I regimen of revised national tuberculosis control program Thirty cases were treatment after lost to followup Twentyone cases were coinfected with tuberculosis and human immune deficiency virusConclusion Treatment outcome was available in 275 patients Out of which 16 cases completed treatment 106 were cured 55 cases stopped treatment 84 died treatment was stopped in 3 patients due to some reason and 11 cases were switched to extensively drug resistant tuberculosis XDR regimen Our study concluded that despite adequate drugs with wellorganized program the treatment outcome of MDR tuberculosis was still low Keywords Multidrug tuberculosis Drug resistant tuberculosis center Programmatic management of drug resistant tuberculosis Extensively drug resistant tuberculosis
Authors and Affiliations
Prashanth Chikkahonnaiah, H. M. Virupaksha
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