REVIEW ON IN-VITRO ANTIOXIDANT SCREENING ASSAYS
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 9
Abstract
Oxygen, an element indispensable for life, can under certain circumstances, adversely affect the human body. The oxygen consumption inherent in cell growth leads to the generation of a series of reactive oxygen species (ROS). The role and beneficial effects of antioxidants against various disorders and diseases induced by oxidative stress have therefore received much attention. The free radical scavenging antioxidants are one of the important classes of antioxidants and the assessment of their capacity has been the subject of extensive studies and argument. This stimuli article reviews the different in-vitro methods for the estimation of the antioxidant capacity. All the models are described along with the different standards that can be used for the estimation.
Authors and Affiliations
Maryam Bincy Thomas*| Department of Pharmacology, Sunder Deep Pharmacy College, Ghaziabad, UP, India- 201001., Lalit Singh| Department of Pharmacology, Sunder Deep Pharmacy College, Ghaziabad, UP, India- 201001., S. K. Sharma| Department of Pharmacology, Sunder Deep Pharmacy College, Ghaziabad, UP, India- 201001.
ETHOSOMES: A NOVEL APPROACH IN TRANSDERMAL DELIVERY OF THE DRUGS
Skin acts as a major target as well as a principal barrier for topical/transdermal drug delivery. Despite the many advantages of this system, the major obstacle is the low diffusion rate of drugs across the stratum corne...
SEROLOGICAL DIAGNOSIS OF HAV AND HEV AND THEIR PREVALENCE IN CLINICALLY SUSPECTED CASES OF ACUTE VIRAL HEPATITIS
NTRODUCTION: ‘Viral Hepatitis’ denotes a primary infection of liver by heterogeneous group of Hepatitis virus. They are clinically indistinguishable, leading to morbidity and mortality. Mainly diagnosed by serological an...
Knowledge, attitude and practice of ADR reporting among clinical residents: A rural medical college survey
Introduction: Pharmacovigilance practices have persistently suffered from under-reporting of ADRs by the clinicians. The present study was done to assess the knowledge, attitude and practices of clinical residents toward...
A review on self emulsifying drug delivery system: promising approach to enhance bioavailability
Among the approaches to improve the oral bioavailability of the molecules, the use of self-emulsifying drug delivery system has been shown to be reasonably successful in improving the oral bioavailability of poorly water...
DERMAL TRANSPORT OF MACRO-MOLECULE MEDICINES
These delivery techniques may be perfect; they do have numerous weaknesses when contrasted with infusions. For instance, oral administration requires proficient assimilation through the gastrointestinal (GI) tract. In th...