Risk Factors of Pancreatic Carcinoma in Rural Area: Case Control Study
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 2
Abstract
The risk factors of pancreatic carcinoma was poorly understand, especially in our country as there were no proper studies done in our country. The main purpose of this study to know the risk factors of pancreatic carcinoma in rural India. OBJECTIVES - There are many well established risk factors for pancreatic carcinoma like chronic pancreatitis, diabetes mellitus, tobacco smoking and alcohol consumption. We have studied the independent effects of these multiple risk factors for pancreatic carcinoma. METHODS – We conducted a case control study involving 40 patients with clinically diagnosed pancreatic carcinoma and 40 frequency matched controls. RESULTS – Chronic pancreatitis, diabetes mellitus, tobacco smoking and alcohol consumption were significant risk factors for the pancreatic carcinoma. Approximately 42.5%, 62.5%, 60%, 55% of pancreatic carcinoma patients in this study were belong to chronic pancreatitis, diabetes mellitus, smoking and alcohol respectively. The risk of developing pancreatic carcinoma in chronic pancreatitis, diabetes mellitus, tobacco smoking was 5, 3.5, 5, and 5 respectively. By multivariate analysis of binary logistic regression chronic pancreatitis and diabetes mellitus were found to be the risk factors of pancreatic carcinoma. CONCLUSIONS – chronic pancreatitis, diabetes mellitus, tobacco smoking and alcohol consumption (>60ml ethanol/day) are proven to be the most established risk factors for pancreatic carcinoma.
Authors and Affiliations
Avinash Gurujala
Keywords
Related Articles
- EP ID EP209358
- DOI -
- Views 70
- Downloads 0
Effect of Melatonin in High Sugar Diet fed Male Wistar rats on the levels of Plasma Glucose, Magnesium, and interleukin-6
Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder in which there is insulin resistance and it is experienced by insulin sensitive tissues like skeletal muscle, adipose tissue, liver, and small part of cardiac tissu...
A Case Report: Sirenomelia
Sirenomelia is a rare and lethal congenital anomaly with an incidence of one in 60,000 to 100,000 pregnancies .The characteristic features of sirenomelia is complete fusion of lower limbs and commonly associated with ren...
Literature Review of Electroencephalography
The research developments of EEG are reviewed in this paper. The major classes of investigations are classified into rehabilitation which includes (i) EEG diseases, (ii) Causes for EEG diseases, (iii) Symptoms for EEG di...
Clinical Profile of Acute Kidney Injury: A Comparative Study of Rifle Vs Akin Criteria
Acute kidney injury (AKI) is a worldwide clinical dilemma encountered in critically ill patients and characteristically portends an increase in morbidity and mortality. Objective: To study prospectively the clinical spec...
Evaluation of Adverse Drug Reactions in teaching hospital in Kumoun Region
Objective: The main aim of the study was to assess the occurrence and pattern of ADRS , assess causality and documentation of Suspected ADRS, inteaching hospital in Kumoun Region. Methods: It is a retrospective study abo...