Risk of developing retinopathy of prematurity in infants varying in hematological parameters, gestational age and some treatment-related factors
Journal Title: Офтальмологический журнал - Year 2018, Vol 0, Issue 4
Abstract
Background: Investigating risk factors for severe retinopathy of prematurity (ROP) is important, given the prevalence of ROP. Purpose: To determine the association of severe ROP with hematological parameters, gestational age and some treatment-related factors. Materials and Methods: The investigation involved a retrospective analysis of some hematological parameters (red blood cell (RBC), white blood cell (WBC) and platelet counts (PLC)) in 1248 preterm neonates. Hematological results were (a) abstracted from neonates’ medical records kept while infants were staying in neonatal care units, and (b) compared with Children’s Reference Ranges for Routine Hematology Tests at age 1 month. Statistical analyses were performed using Medstat Software version 16.8.4. Models were developed and analyzed using EZR version 1.32. Results: We found the following independent variables to be associated with an increased risk of severe ROP: low gestational age (OR, 0.52; 95% CI, 0.45 – 0.60; p < 0.001), mechanical ventilation (OR, 2.9; 95% CI, 1.4 – 5.9; p = 0.003), blood transfusion (OR, 1.23; 95% CI, 1.03 – 1.49; p = 0.02), and thrombocytopenia (OR, 0.72; 95% CI, 0.60 – 0.87; p < 0.001). Conclusion: Values of these independent variables should be taken into account when performing longitudinal screening for ROP.
Authors and Affiliations
S. Katsan, A. Adakhovska
Keywords
Related Articles
- EP ID EP423680
- DOI 10.31288/oftalmolzh201842631
- Views 89
- Downloads 0
Metabolic correction of experimental diabetic retinopathy
Introduction. Diabetic retinopathy (DR) is diagnosed in 50% of the total number of patients suffering from type 1 diabetes mellitus with diabetes duration of over 10 years and in 75-90% of patients with diabetes duration...
Substantiating the potential for a new technique (impedance oculopneumoplethysmography) to assist in diagnosing microvascular ciliary body ischemia
Purpose: To provide theoretical substantiation of the potential for a new technique, impedance oculopneumoplethysmography (OPPG), to assist in diagnosing microvascular ciliary body ischemia. Methods: Modeling the distri...
Thea (France) – TROPHY: a contest for residents or fellows in ophthalmology
The Chibrets is a famous name in the pharmaceutical ophthalmology, not only in Europe, but far beyond. Five generations of the family dedicated themselves to innovative research and development for advanced stability and...
Relationship of the recurrence after pterygium surgery with the presence of HSV, EBV, CMV, HPV, and BRAFV600E mutation
Background: Previously, we have reported on associations of pterygium with the presence of herpes simplex virus (HSV), Epstein Barr virus (EBV), cytomegalovirus (CMV), human papillomavirus (HPV), and the BRAFV600E somati...
Patterns of development of retinal vascular pathology at remote time period after radiation exposure
Background. Retinal vascular system is extremely sensitive to ionizing radiation exposure and requires priority medical examination. Probability of new accident environmental contamination with radioactive material is a...