RNA Interference: An Evolutionary Pathway in Periodontal Tissue Engineering
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2016, Vol 6, Issue 1
Abstract
RNA interference (RNAi) is an evolutionary conserved silencing pathway in which the double-stranded RNA is broken down into small interfering RNA (siRNA) with the help of dicer and RNA-induced silencing complex (RISC) complex by a series of steps. Pioneering observations on RNAi were reported in plants, but later on RNAi-related events were described in almost all eukaryotic organisms, including protozoa, flies, nematodes, insects, parasites, and mouse and human cell lines
Authors and Affiliations
Swyeta Jain Gupta
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