Role of 3D FLAIR in Demonstration of Peripheral Lesions of Brainstem and Cranial Neuropathies

Journal Title: International Neuropsychiatric Disease Journal - Year 2014, Vol 2, Issue 4

Abstract

Aim: We present a pictorial review of 3D FLAIR images depicting its importance in demonstrating the peripheral lesions of brainstem particularly in relation to attachment of cranial nerves and cranial neuropathies and particularly in context of patients with multiple sclerosis (MS). Discussion: T2 axials and routine 2D FLAIR have drawbacks in depicting the lesions on the peripheral aspects of brainstem. Such lesions are commonly found in MS. The revised McDonald’s criteria (2010) put equal emphasis on periventricular, juxtacortical, infratentorial and cord lesions. Detection of peripheral lesions thus play important role in fulfilling the criteria of dissemination in space and also provide anatomic correlate in several cranial nerve palsies. In clinically isolated syndromes, demonstration of lesions at the site of affected cranial nerves increase diagnostic confidence and exclude other potential disease processes. Ability to show signal changes at cranial nerve attachment can also potentially prevent a false attribution of symptoms to neurovascular compression. Conclusion: We propose that 3D FLAIR sequence is extremely useful in detecting abnormalities on the surface of brainstem and cranial nerve attachments and should be performed in all patients of MS and cranial nerve palsies.

Authors and Affiliations

Avinash Kumar Kanodia, Graeme MacKenzie, Pheyming Yeap, Jonathan O. Riordan, Richard Stephen Nicholas, Gavin Main

Keywords

Related Articles

Desmoplastic Medulloblastoma Patients Survival after Multimodality Treatment

Aims: This is to investigate the results of the multimodality regimen including surgery, postoperative craniospinal irradiation and clarify the role of chemotherapy as well as the influence of multiple variables on desmo...

Mindfulness, Sexual Functioning, and Subjective Sexual Well-Being

Although there are several studies that address mindfulness, sexual functioning, and subjective sexual well-being separately, there are very few studies that explore the associations between these three constructs. There...

Prenatal Exposure to Maternal Anxiety is Associated with Less Developed Smooth Pursuit Eye Movements in Six-Month-Old Infants: An Initial Study

Aims: There are an increasing number of reports suggesting an association between maternal anxiety experienced during pregnancy and adverse outcomes of the offspring. However, exploration of the biological changes in the...

Life Satisfaction, Self Esteem and Depression in a Sample of Nigerian Adolescents

Background: A person’s state of mind often affects his/her health and how he/she responds to stress. The level of happiness and life satisfaction in the individual can be assessed by finding out if a person has high amou...

Cotard’s Syndrome: Clinical Case Presentation and Literature Review

In 1880 French neurologist Jules Cotard described a condition characterized by delusion of negation (nihilistic delusion) in a melancholia context. Recently, there has been a resurgence of interest in Cotard’s syndrome....

Download PDF file
  • EP ID EP241517
  • DOI 10.9734/INDJ/2014/8190
  • Views 88
  • Downloads 0

How To Cite

Avinash Kumar Kanodia, Graeme MacKenzie, Pheyming Yeap, Jonathan O. Riordan, Richard Stephen Nicholas, Gavin Main (2014). Role of 3D FLAIR in Demonstration of Peripheral Lesions of Brainstem and Cranial Neuropathies. International Neuropsychiatric Disease Journal, 2(4), 167-174. https://europub.co.uk./articles/-A-241517