Role of antibiotic loaded acrylic bone cement in orthopedic infection
Journal Title: National Journal of Clinical Orthopaedics - Year 2018, Vol 2, Issue 3
Abstract
Introduction: Local antibiotic delivery with antibiotic loaded acrylic bone cement has been used extensively in the management of chronic osteomyelitis and implant related infections. It is considered the gold standard for treatment of musculoskeletal infections (Nelson, 2004). Over the past few decades, attempts have been made to prevent and cure orthopedic implant infections by incorporating antibiotics in polymethylmethacrylate bone cements, in primary and revision surgery. Antibiotic loaded bone cement (ALBC) is popular as it is a proven way to deliver high concentrations of the drug locally, even to avascular areas that are inaccessible by systemic antibiotics. This article review the role of antibiotic loaded acrylic bone cement beads in orthopaedic trauma. Materials & Methods: This is a Prospective, Non Randomized study carried out in 40 patients posted for orthopaedic procedures. For evaluating the functional outcome of treatment we used the Asepsis Wound Score. Total duration of study is 6 to 9 months. Results: The mean age of the patient was 40 years (range 20-50 yrs). Incidence of fracture was observed maximum between 40- 50 years of age. Among the 40 cases, males were predominant. We observed predominance Staphylococcus Organism in Pus Culture. Out of 40 cases 53% cases was open fractures and 70% cases were RTA. Conclusion: The theoretical advantages of antibiotic-impregnated cement and cement beads in the treatment and prophylaxis of orthopedic infections are supported by the results of some studies but Evidence of their efficacy, particularly in comparison with those of systemic antibiotics or with those of antibiotic-impregnated cement or beads in combination with systemic antibiotics, have not been firmly established. In our study there was marked decrease in infection rate by using antibiotic cemented beads but certain infection like Chronic osteomyelitis is often a lifelong disease. Despite all of the advances in antibiotic and operative treatment, osteomyelitis remains difficult to treat.
Authors and Affiliations
Dr. Punit J Tank, Dr. Vishal A Pushkarna, Dr. Sheetal Gamit
Keywords
Related Articles
- EP ID EP506911
- DOI -
- Views 60
- Downloads 0
Assessment of outcomes of locking compression plates for fractures of distal end of femur
Objective: To evaluate the result of locking compressive plate in different types and severity of distal femoral fractures both clinically and radiologically. Methods: 40 male and 10 female patients aged 18 to 85 (mean 3...
Study of outcomes of supracondylar Humerus fracture with ipsilateral lower end radius fracture in children
Supracondylar humerus fracture with forearm fractures are rare with reported incidence ranging from 3% to 13%. We have treated ten patients with ipsilateral supracondylar humerus fracture with distal radius fracture. One...
Open reduction internal fixation with plating versus external fixator in distal end radius fractures: A comparative study
Introduction: Low energy falls leading to stable variety of fracture patterns are seen most commonly, but young patients tend to have a high-energy mechanism of injury. Nonsurgical management remains main line of managem...
To study the outcome of intercondylar fractures of distal humerus using dual plating and its functional outcome
Introduction: Distal humeral fractures account for approximately 2%–6% of all fractures and for approximately 30% of all elbow fractures [1]. The complex anatomy of the distal end of the humerus, with its unique orientat...
Management of proximal humeral fractures with philos locking plate: A prospective study
Introduction: Proximal humeral fractures are the second most common fractures of the upper extremity accounting for 4% to 5% of all fractures. The treatment of proximal humeral fractures is divided into non-operative and...