Role of Candida in Catheter Associated Urinary Tract Infection
Journal Title: International Journal of Current Research and Review - Year 2018, Vol 10, Issue 20
Abstract
Background: UTI in hospitalised patients due to Candida spp. is becoming increasingly common in ICU setting. There is always a dilemma as to differentiate colonisation from true infection and whether to treat candiduria or not. The choice of antifungal is also controversial due to low urinary concentration of many antifungal drugs. Objective: This study was conducted to assess the significance of Candida spp. as the causative agent of symptomatic CAUTI in medical ICU patients and perform microbiological characterisation of Candida and their antifungal susceptibility pattern. Methods: A total of 100 patients admitted in medical ICU and put on Foley’s catheter were included in the study and followed up for the development of symptomatic CAUTI. The urine samples from the catheter were collected on day 1 and then on day 3,5,7,10,14 and every weekly till the patient was discharged, expired, catheter removed or developed bacteriuria or candiduria. The samples positive for Candida spp. were identified and processed as per standard guidelines. Results: In this study, it was found that 23% (6/26) of the symptomatic CAUTI was caused by Candida spp. Candida species comprised 15% of the causative organisms. Among the candida species, non-albicans Candida spp. contributed to 83.3% of the isolates and only 16.7% of isolates were Candida albicans. All Candida isolates were sensitive to fluconazole, voriconazole, amphotericin B and itraconazole. Conclusion: Symptomatic catheter associated urinary tract infection with Candida spp. is becoming increasingly common. Among Candida spp., non-albicans Candida is emerging as the predominant pathogen causing CAUTI.
Authors and Affiliations
Dr. Swati Sahai
Keywords
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- EP ID EP536149
- DOI 10.31782/IJCRR.2018.10204
- Views 113
- Downloads 0
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