ROLE OF CEREBROPROTEIN HYDROLYSATE IN OUTCOME AND RECOVERY OF TRAUMATIC BRAIN INJURY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 18
Abstract
BACKGROUND Traumatic Brain Injury (TBI) is a complex injury with a wide range of symptoms and disabilities, which can lead to a lifelong devastating effect on the patient and the family. Its (TBI) incident is increasing day-by-day. There is a need of better management in traumatic brain injury patient to reduce the mortality and associated with it. Cerebroprotein hydrolysate is a recent neurotrophic and neuroprotective drug which is in use for acute ischaemic strokes, vascular dementia, Alzheimer’s disease and traumatic brain injuries with its proven potential. Aims and Objectives- Our work aims to evaluate the effectiveness and safety of cerebroprotein hydrolysate in the management of brain injury patients. MATERIALS AND METHODS A randomised controlled trial used in the study and the sample size was taken for convenience during the study. This study was conducted on 200 patients and the patients were randomly divided into two groups. Group 1 (study group, n= 100) received cerebroprotein hydrolysate for 14 - 21 days and Group 2 (control group, n= 100) received only conventional therapy. Both the groups were assessed with GCS (Glasgow Coma Score), APACHE Π (Acute Physiology and Chronic Health Evaluation II) scores and CT/ MRI Brain on admission and were compared in terms of degree of improvement on 14 - 21 days from the day of admission. RESULTS Patient on cerebroprotein hydrolysate was compared to conventional therapy (control) group. Patients with cerebroprotein hydrolysate showed statistical significance (p value= 0.001) in regard to GCS and in terms of functional and cognitive outcome. CONCLUSION Our study concludes that the usage of cerebroprotein hydrolysate therapy can be safe and useful in traumatic brain injury in terms of functional and cognitive outcome with better recovery
Authors and Affiliations
Ishwar Dayal Chaurasia, Manish Parihar, Puspendra Gehlot, Ansul Siroliya, Songara M. C
Keywords
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- EP ID EP417267
- DOI 10.14260/jemds/2018/489
- Views 87
- Downloads 0
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