Role of DXA in Diagnosis and Assessment of Fracture Risk in Osteoporotic Patient.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Introduction: Osteoporosis has operationally defined by the WHO on the basis of bone mineral density (BMD) assessment. Dual-energy X-ray absorptiometry (DXA) is a means of measuring bone mineral density (BMD). The DXA scan is typically used to diagnose and follow osteoporosis. DXA scans to measure BMD at the spine and hip have an important role in the evaluation of individuals at risk of osteoporosis, and in helping clinicians advice patients about the appropriate use of anti-fracture treatment. Compared with alternative bone densitometry techniques DXA have number of advantages. FRAX is a computer-based algorithm that employs bone density, age and a number of clinical risk factors to help patients and their doctors predict the likelihood of having a fracture in the next 10 years. Objective: To predict fracture risk in osteoporotic men and women with the use of clinical risk factors for fracture and femoral neck T-score with the help of FRAX score. Method: FRAX tool is used assess fracture risk with the help of T-score with and knowing CRF’s from 400 men and women drawn from the general population with age more than 40 years. Results: Out of 400 individuals 140 were found to be osteoporotic with T-score < -2.5 and FRAX score is calculated which show >3% chances of hip fracture in 66.43% individuals and >20% chances of other major osteoporotic fracture in 12.86% individuals. Conclusion: In elderly men and women it is showed that low BMD is a major risk factor for fracture and incorporation of CRFs improves the operating characteristics of fracture risk assessment over.
Authors and Affiliations
Dr. Manoj Kumar Verma, Dr. Sushant Verma
Evaluation of DNA damage levels in Oral leukoplakia by Single Cell Gel Electrophoresis Assay
: Comet assay also known as Single cell gel electrophoresis (SCGE) assay is a rapid and highly sensitive fluorescent molecular technique for detecting various forms of deoxyribonucleic acid (DNA) damage at individual cel...
Effects of Different Bleaching Agents on Micro-Hardness and Color Changes in Human Enamel
Objectives: This single-blind in-vitro study was conducted to assess the effect of different in-office and home bleaching agents on the micro-hardness and color changes of dental enamel. Materials and Methods:Twenty huma...
Functional Outcome of Bimalleolar Ankle Fractures Treated With Semitubular Plate for Lateral Malleolus and Malleolar Screws for Medial Malleolus
Background: Malleolar injuries are the most common significant lower extremity fractures. These injuries gain importance, because the whole body weight is transmitted through the ankle, and locomotion depends on the stab...
Proteomics:A New Diagnostic Horizon In Periodontics.
Periodontitis is an inflammatory condition resulting from the interplay between the infectious agents and host factors. Various protein molecules play a vital role in the initiation, progression and severity of periodont...
Application of Tops Score in Sick Neonates Received At Level 3 Nicu and Its Impact on the Outcome of the Neonate
Transporting of neonates is the greatest challenge faced today in the outcome of neonates in our country. We have scarce and inaccessible facilities, no any accomplice for enroute and underdeveloped communication system....