Role of Fine Needle Aspiration Cytology [FNAC] in diagnosis of Thyroid lesions
Journal Title: Journal of Contemporary Medicine and Dentistry - Year 2017, Vol 5, Issue 1
Abstract
Background: FNAC of the thyroid gland is now a well established first line diagnostic test for the evaluation of diffuse as well as nodular lesions of thyroid. The main purpose of FNAC is confirming benign lesions and thereby reducing unnecessary surgery. Objectives: this study was aimed at evaluating experience of FNAC and correlating the findings with tissue biopsy – in the diagnosis of thyroid lesions. Methods: Patients with neck swellings attending medical, surgical and ENT outpatient clinics and wards with thyroid lesions were sent to department of pathology, PIMS Hospital, Karimnagar where FNAC was done. Before aspiration, a detailed history and clinical examination was done. FNAC was performed in all cases using 23 Gauge Needle aached to 20 ml disposable syringe. Smear was prepared on standard glass slides fixed and stained with H&E or MGG stains. Results: A total of 66 cases were included in the study. Majority of cases were reported as benign lesions by FNAC n=58 (87.88%) and Histopathology showed n=60 (90.91) as benign lesions. The percentage of malignant lesions reported by FNAC was n=8 (12.12%) and by histopathological examinaon n=6 (9.09%) were reported as malignant lesions. The sensivity was calculated at 96.67% and the specificity was 96.77% the PPV value was 90.61% and the NPV was 96.77%. Conclusions: FNAC is it is a cost effective procedure which can be performed on outpatient basis and it can be repeated due to patient acceptance. Its sensitivity and specificity are within acceptable range provided standard protocol is adopted. It bridges the gap between clinical evaluation and histopathologic diagnosis in majority of cases.
Authors and Affiliations
K. Shyam Sunder, Mohd Inayatulla Khan
Keywords
Related Articles
- EP ID EP447186
- DOI -
- Views 112
- Downloads 0
Ulipristal Acetate- A Selective Progesterone Receptor Modulator
Background: Unintended pregnancies occur due to unprotected sexual intercourse. To avoid such unplanned pregnancies emergency contraceptives are available. Ulipristal acetate is one such orally active drug which is a sel...
Protective Role of Olive Oil and Polyherbal Drug on Renal Dysfunction Induced by Dexamethasone in Albino Rats
This study was plan to evaluate the biochemical effects of olive oil and polyherbal drug against dexamethasone-induced renal dysfunction in a male albino rat. Male rats (20) were divided into four equal groups: Group 1:...
Pterion formation and its variations in Human Skull in Vidarbha Region
Introduction: The study aims to analyze for the location and types of pterion in adult skulls of Vidarbha region of Maharashtra. Materials & Methods: Study was performed on 350 adult human skulls. The pterion types were...
Estimation of Serum Immunoglobulins [IgG] and [IgA] in Patients with Grade III and Grade IV Oral Submucous Fibrosis
Background: The present study was done to estimate the serum levels of IgG and IgA in patients of grade III and grade IV oral submucous fibrosis. Materials &Methods: A total of 189 patients of both sexes of OSMF of grade...
Evaluation of Bacterial Contamination of Old and New Indian Paper Currency Notes
Background: Currency is widely exchanged for goods and services. It gets contaminated during handling. Contaminated currencies might act as fomites, playing an important role in the transmission of microorganisms. Since...